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2022 ◽  
Vol 12 (1) ◽  
pp. 35-42 ◽  
Mevan Salih Rasheed ◽  
James Yohana Odeesh ◽  
Toreen Ahmad Ibrahim

This research seeks to contribute to the retention Duhok kidney & diseases transplantation center (DKDTC), and health organizations their talent in COVID-19 era. To achieve this objective, we use (IBM SPSS Amoss V.22) to analyze the mediating role of career planning (CP) in the relationship of financial compensation (FC) with talent retention (TR) in DKDTC. The data collected was analyzed through 63 questionnaires, which was distributed to the talents working in DKDTC from May 2020 to March 2021. The researchers reached several conclusions, the most important of which are that CP has a partial mediating role in the relationship between FC and TR. Therefore, this research recommends enhancing the ability of DKDTC and health organizations to TR in a COVID-19 era and they must be relying on FC, and a program that includes clear steps in CP.

Zootaxa ◽  
2021 ◽  
Vol 5040 (2) ◽  
pp. 238-246

We studied the relationship of the genera Loxoblemmus Saussure, 1877 and Asonicogryllus He, 2019 by reconstructing the phylogenetic tree based on 2 mitochondrial genes and 2 ribosomal genes. The result shows that Loxoblemmus is paraphyletic. Thus, we place Asonicogryllus as a subgenus of Loxoblemmus. Meanwhile, we report a new species of Asonicogryllus, L. (A.) bronzus He sp. nov. The new species is similar to L. (A.) kwanghua, but it has well developed forewings and hindwings. The type specimens are deposited in the Museum of Biology, East China Normal University (ECNU).  

2021 ◽  
Anver Sverguzov

From the point of view of the dialectical-materialistic approach, the central ontological problem is analyzed — the problem of the existence of matter. For researchers specializing in the direction 09.00.01 "Ontology and theory of knowledge", as well as all those interested in philosophy.

PLoS Genetics ◽  
2021 ◽  
Vol 17 (9) ◽  
pp. e1009816
Salar Ahmad ◽  
Valérie Côté ◽  
Xue Cheng ◽  
Gaëlle Bourriquen ◽  
Vasileia Sapountzi ◽  

The NuA4 histone acetyltransferase complex, apart from its known role in gene regulation, has also been directly implicated in the repair of DNA double-strand breaks (DSBs), favoring homologous recombination (HR) in S/G2 during the cell cycle. Here, we investigate the antagonistic relationship of NuA4 with non-homologous end joining (NHEJ) factors. We show that budding yeast Rad9, the 53BP1 ortholog, can inhibit NuA4 acetyltransferase activity when bound to chromatin in vitro. While we previously reported that NuA4 is recruited at DSBs during the S/G2 phase, we can also detect its recruitment in G1 when genes for Rad9 and NHEJ factors Yku80 and Nej1 are mutated. This is accompanied with the binding of single-strand DNA binding protein RPA and Rad52, indicating DNA end resection in G1 as well as recruitment of the HR machinery. This NuA4 recruitment to DSBs in G1 depends on Mre11-Rad50-Xrs2 (MRX) and Lcd1/Ddc2 and is linked to the hyper-resection phenotype of NHEJ mutants. It also implicates NuA4 in the resection-based single-strand annealing (SSA) repair pathway along Rad52. Interestingly, we identified two novel non-histone acetylation targets of NuA4, Nej1 and Yku80. Acetyl-mimicking mutant of Nej1 inhibits repair of DNA breaks by NHEJ, decreases its interaction with other core NHEJ factors such as Yku80 and Lif1 and favors end resection. Altogether, these results establish a strong reciprocal antagonistic regulatory function of NuA4 and NHEJ factors in repair pathway choice and suggests a role of NuA4 in alternative repair mechanisms in situations where some DNA-end resection can occur in G1.

2021 ◽  
Vol 21 (1) ◽  
Wei Dong ◽  
Jia Zeng ◽  
Qin Wang ◽  
Xin Jiang ◽  
Ting Huang

Abstract Background Siraitia grosvenorii (binomial name Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang), also called Arhat Fruit or Monk’s Fruit, is a dried ripe fruit belonging to the Cucurbitaceae Family. S. grosvenorii has a long history of being used for constipation treatment in folk medicine. However, there are few studies where the laxative effect, related mechanisms, and active constituents of S. grosvenorii were investigated. This research explores the relationship between the common components and the laxative effect of aqueous extracts of S. grosvenorii from different habitats in China. Methods The fingerprints of S. grosvenorii aqueous extracts from different habitats were established by HPLC. The constipation mice model was used to investigate the laxative effect of S. grosvenorii aqueous extracts. The motilin (MTL) level in mice serum, and the water content of the large and small intestines in mice were determined. The profile-effect relationship of S. grosvenorii aqueous extracts was preliminarily clarified using gray correlation analysis. Results Nine common peaks were identified from the fingerprint of aqueous extracts of S. grosvenorii. The aqueous extracts obviously shortened the incubation period of defecation, and significantly increased the number of defecations, and the wet and dry weight of defecation in constipated mice. The profile-effect relationship indicated that seven common peaks were highly correlated with the effect of the incubation period of defecation, the number of defecations, and the wet and dry weight of defecation in mice. Conclusion This work provides a promising method for the fingerprint establishment, pharmacodynamic evaluation, and quality control of S. grosvenorii on the basis of its profile-effect relationship.

2021 ◽  
Vol 1 (9) ◽  
pp. 850-857
Adina Fairuz

This study discusses the relationship between costume design in films and the interest of the audience, especially young adult women, triggers of their interest in similar fashion products as consumers by using outfit styles from three films, The Devil Wears Prada (2006), Sex and The City: The Movie (2008) and Crazy Rich Asians (2018), which were selected through a questionnaire answered by 20 experts in the fashion field. The analysis was conducted on 258 young adult women (18-24 years old) domiciled in Indonesia through a questionnaire to find out their perceptions and preferences on outfit styles from the costume designs in those three films. Based on this analysis, it can be seen that if the audience is interested and feels that the outfit worn by the character fits them, then they will have the desire to wear fashion products that are similar to the appearance of the costume design in the film.

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Shakir Karim ◽  
Zaheeruddin Asif

The quality of tasks performed by a crowd worker is questionable. Most of the workers are lost if their first work is of low quality, which may influence them to acquire future work in crowdsourcing. Research has highlighted that workers either lack motivation or capability. However, the integrative perspective of capability and motivation in current crowdsourcing research is scarce. There is a need to investigate the relationship of capability and motivation of crowd worker to understand the phenomenon of getting better performance, which ultimately produces a quality outcome. This research aims toward understanding such relationship with mathematical perspective. The traditional renowned and well-accepted theories related to job performance are used for the quantification of motivation, capability, and performance for crowd workers to investigate the impact of capability in relation to the motivation on the performance of crowd worker. Experimental results suggest that formulae will benefit the requester to evaluate the performance of a crowd worker before providing him/her the task and benefit in reducing unemployment in the situation of COVID-19 pandemic.

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Pooja Mehta ◽  
Manjit Singh ◽  
Manju Mittal ◽  
Himanshu Singla

Purpose This study aims to test the serial mediation effect of attitude toward socially responsible investing (SRI) and social investing efficacy (SIE) on the relationship of knowledge about SRI with the intention to invest in SRI along with moderating effect of religiosity. Design/methodology/approach The study uses a quantitative analysis approach, wherein the data has been collected from 569 north Indian retail investors. Partial least square (PLS)-structural equation modeling has been applied in this study using the latest version of SmartPLS (v. 3.2.8) software to examine the complex model of serial and moderated mediation. Findings Attitude toward SRI and SIE significantly and serially mediate the relationship between knowledge about SRI and intention to invest in SRI. Also, the interaction effect of religiosity with knowledge about SRI is significant only for SIE and not for attitude toward SRI. Research limitations/implications The study is cross-sectional in nature conducted only on the north Indian investors. Besides knowledge, there can be many other personal or social aspects that might affect SRI intention that have not been taken into the study. Practical implications The results suggested that the companies, financial advisors and governmental bodies can improvise upon social and environmental performance reporting so that investment in SRI can be promulgated. Social implications The paper concludes that religious-minded people are more open to the idea of investing in SRI. India, being is a religious-minded country, the results of this study suggest that there is good potential for the development of SRI in India. Originality/value Empirical evidence regarding the relationship of SRI intention with its determinants is limited in Asian countries. Prior literature mainly provides evidence from developed countries where social and governance systems are comparatively stronger. The study provides evidence for the bright future of SRI in India, where investor’s beliefs are dominated by their religious values.

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