Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin-Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)

Angewandte Chemie International Edition ◽

10.1002/anie.200501428 ◽

2005 ◽

Vol 44 (37) ◽

pp. 5944-5967 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Nobel Lecture ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

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Intracellular Protein Degradation: From a Vague Idea, Through the Lysosome and the Ubiquitin—Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)

10.1002/chin.200549272 ◽

2005 ◽

Vol 36 (49) ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Nobel Lecture ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular Protein Degradation From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and on to Human Diseases and Drug Targeting: Nobel Lecture, December 8, 2004

Annals of the New York Academy of Sciences ◽

10.1196/annals.1402.078 ◽

2007 ◽

Vol 1116 (1) ◽

pp. 1-28 ◽

Author(s):

A. CIECHANOVER

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Nobel Lecture ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin-Proteasome System, and onto Human Diseases and Drug Targeting Nobel Lecture

Israel Journal of Chemistry ◽

10.1560/380v-vwlx-xdrt-cb7k ◽

2006 ◽

Vol 46 (2) ◽

pp. 121-136 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Nobel Lecture ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular Protein Degradation: From a Vague Idea Thru the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting*

Experimental Biology and Medicine ◽

10.1177/153537020623100705 ◽

2006 ◽

Vol 231 (7) ◽

pp. 1197-1211 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting

Neurodegenerative Diseases ◽

10.1159/000334283 ◽

2012 ◽

Vol 10 (1-4) ◽

pp. 7-22 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ◽

10.1016/j.bbapap.2011.03.007 ◽

2012 ◽

Vol 1824 (1) ◽

pp. 3-13 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

Best Practice & Research Clinical Haematology ◽

10.1016/j.beha.2017.09.001 ◽

2017 ◽

Vol 30 (4) ◽

pp. 341-355 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting

Rambam Maimonides Medical Journal ◽

10.5041/rmmj.10068 ◽

2012 ◽

Vol 3 (1) ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular protein degradation: From a vague idea through the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.01.056 ◽

2013 ◽

Vol 21 (12) ◽

pp. 3400-3410 ◽

Author(s):

Aaron Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Cell Death and Differentiation ◽

10.1038/sj.cdd.4401692 ◽

2005 ◽

Vol 12 (9) ◽

pp. 1178-1190 ◽

Author(s):

A Ciechanover

Keyword(s):

Protein Degradation ◽

Drug Targeting ◽

Ubiquitin Proteasome System ◽

Human Diseases ◽

Intracellular Protein ◽

Intracellular Protein Degradation ◽

Ubiquitin Proteasome

Download Full-text