scholarly journals Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery

BJS Open ◽  
2018 ◽  
Vol 2 (4) ◽  
pp. 185-194 ◽  
Author(s):  
S. T. McSorley ◽  
C. W. Steele ◽  
A. J. McMahon
Keyword(s):  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation ◽  
Surgical Site Infections ◽  
Oral Antibiotics ◽  
Elective Colorectal Surgery ◽  
Intravenous Antibiotics

scholarly journals EP.TH.965Use of Oral Antibiotics as Adjunct to Systemic Antibiotics and Mechanical Bowel Preparation for Left Sided Colorectal Surgery. It is the time to trust the best available evidence and change the practice

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Shahin Hajibandeh ◽  
Shahab Hajibandeh ◽  
Christopher Thompson ◽  
Vijay Thumbe ◽  
Andrew Torrance ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Anastomotic Leak ◽  
Bowel Preparation ◽  
Mechanical Bowel Preparation ◽  
Surgical Site Infections ◽  
Oral Antibiotics ◽  
Intravenous Antibiotics ◽  
Clinically Significant ◽  
The Uk ◽  
Systemic Antibiotics

Abstract Aims To prospectively evaluate the clinical efficacy of oral antibiotics as an adjunct to intravenous antibiotics and mechanical bowel preparation (MBP) in patients undergoing left sided colorectal surgery. Methods All participants aged 18 years or older and of any gender undergoing an elective open or laparoscopic left sided colorectal resection for benign or malignant colorectal pathologies were considered. The intervention of interest was oral neomycin 1g every 4 hours combined with oral metronidazole 400mg every 8 hours from 24 hours before the proposed surgery. Surgical site infections (SSIs), anastomotic leak, paralytic ileus, need for intervention, and mortality were the evaluated outcome parameters. Results Forty-two consecutive patients received oral antibiotics as an adjunct to intravenous antibiotics and MBP before left sided colorectal surgery. The mean age was 58.8 ± 11.5. There were 23 males (54.8%) and 19 females (45.2%). Use of oral antibiotics was associated with SSI infection rate of 2.4% (1 patient). The rates of clinically significant and non-significant anastomotic leak were 0% and 2.9%, respectively. Moreover, postoperative ileus happened in 11.9% of patients. Furthermore, there was no mortality or need for re-intervention. Conclusions Use of oral antibiotics as an adjunct to intravenous antibiotics and MBP in patients undergoing left-sided colorectal surgery was associated with a surprisingly low rate of SSIs and no significant anastomotic leak. It is time to trust the best available evidence and incorporate the use of oral antibiotics as an adjunct to intravenous antibiotics and MBP in colorectal surgery protocols in the UK hospitals.

scholarly journals Association of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery With Surgical Site Infection

2018 ◽  
Vol 1 (6) ◽  
pp. e183226 ◽  
Author(s):  
James W. T. Toh ◽  
Kevin Phan ◽  
Kerry Hitos ◽  
Nimalan Pathma-Nathan ◽  
Toufic El-Khoury ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Surgical Site Infection ◽  
Bowel Preparation ◽  
Mechanical Bowel Preparation ◽  
Site Infection ◽  
Oral Antibiotics ◽  
Elective Colorectal Surgery

scholarly journals MODERN VIEW ON DIFFERENT KINDS OF BOWEL PREPARATION FOR ELECTIVE COLORECTAL SURGERY

2019 ◽  
Vol 18 (3) ◽  
pp. 97-102
Author(s):  
A. Yu. Olkina ◽  
A. S. Petrov ◽  
L. L. Panaiotti ◽  
A. М. Karachun ◽  
T. S. Lankov
Keyword(s):  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Standard Procedure ◽  
Mechanical Bowel Preparation ◽  
Term Treatment ◽  
Current Data ◽  
Oral Antibiotics ◽  
Short Term Treatment ◽  
Elective Colorectal Surgery ◽  
Preoperative Bowel Preparation

Purpose: to assess current data on the effect of different approaches to preoperative bowel preparation before elective colorectal surgery on short-term treatment outcomes.Material and Methods. Online system PubMed of U.S. National Library of Medicine was used to find articles with key words “mechanical bowel preparation”, “surgical site infection”, “oral antibiotics”. A total of 226 articles were reviewed. 31 articles were selected for final review. Furthermore, ClinicalTrials.gov site was used to find actual and recruiting trials.Results. Mechanical bowel preparation (MBP) used to be a standard procedure for a long time. Nowadays, routine use of MBP seems to be debatable. Alternative approaches, e.g. absolutely no preparation or the use of MBP in combination with oral antibiotics, are considered. Data on performing different kinds of bowel preparation is reviewed in this article.Conclusion. Optimal approach of preoperative bowel preparation is still questionable. Combination of mechanical bowel preparation and oral antibiotics seems to be a preferable method. However, there is not enough evidence to exclude anothertechniques. It’s required to conduct additional randomized controlled trials.

scholarly journals Impact of mechanical bowel preparation in elective colorectal surgery: A meta-analysis

2018 ◽  
Vol 24 (4) ◽  
pp. 519-536 ◽  
Author(s):  
Katie E Rollins ◽  
Hannah Javanmard-Emamghissi ◽  
Dileep N Lobo
Keyword(s):  
Colorectal Surgery ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Mechanical Bowel Preparation ◽  
Elective Colorectal Surgery
Sign in / Sign up

Export Citation Format

Share Document