Limitations of the zero crossing detector in the analysis of intracoronary doppler: A comparison with fast fourier transform analysis of basal, hyperemic, and transstenotic blood flow velocity measurements in patients with coronary artery disease

1993 ◽  
Vol 28 (1) ◽  
pp. 56-64 ◽  
Author(s):  
Carlo Di Mario ◽  
Jos R. T. C. Roelandt ◽  
Peter De Jaegere ◽  
David T. Linker ◽  
Jan Oomen ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Blood Flow ◽  
Fourier Transform ◽  
Coronary Artery ◽  
Blood Flow Velocity ◽  
Velocity Measurements ◽  
Zero Crossing ◽  
Fast Fourier Transform Analysis ◽  
Intracoronary Doppler ◽  
Artery Disease

Association between coronary lesion severity and distal microvascular resistance in patients with coronary artery disease

2003 ◽  
Vol 285 (5) ◽  
pp. H2194-H2200 ◽  
Author(s):  
Steven A. J. Chamuleau ◽  
Maria Siebes ◽  
Martijn Meuwissen ◽  
Karel T. Koch ◽  
Jos A. E. Spaan ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Blood Flow ◽  
Coronary Artery ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Guide Wire ◽  
Coronary Lesion ◽  
Artery Disease ◽  
Microvascular Resistance ◽  
Lesion Severity

Homogeneity of microvascular resistance in different perfusion areas of the same heart is generally assumed. We investigated the effect of the severity of an epicardial stenosis on microvascular resistance in 27 patients with coronary artery disease and stable angina. All patients had an angiographically normal coronary artery, an artery with an intermediate lesion, and an artery with a severe lesion; the latter was treated with angioplasty. In each patient, distal blood flow velocity and pressure were measured during baseline and maximal hyperemia (induced by intracoronary adenosine) using a Doppler and pressure guide wire, respectively. The ratio of mean distal pressure to average peak blood flow velocity was used as an index for the microvascular resistance (MRv). Within patients, the hyperemic MRv was higher in arteries with more severe stenosis ( P = 0.021). After percutaneous transluminal coronary angioplasty (PTCA), the hyperemic MRv decreased (pre-PTCA, 2.6 vs. post-PTCA, 1.9 mmHg·cm–1s–1, P < 0.01) toward the value of the reference artery (1.7 mmHg·cm–1s–1; P = 0.67). We conclude that there is a positive association between coronary lesion severity and variability of distal microvascular resistance that normalizes after angioplasty. This study challenges the concept of uniform distribution of hyperemic MRv that is relevant for the interpretation of both noninvasive and invasive diagnostic tests.

scholarly journals Role of transmittal blood flow velocity by doppler echocardiography in the evaluation of coronary artery disease

1990 ◽  
Vol 13 (2) ◽  
pp. 108-114 ◽  
Author(s):  
C. Brunckhorst ◽  
H. W. Lange ◽  
W. Aschenberg ◽  
W. Rehpenning ◽  
W. Bleifeld
Keyword(s):  
Coronary Artery Disease ◽  
Blood Flow ◽  
Coronary Artery ◽  
Flow Velocity ◽  
Doppler Echocardiography ◽  
Blood Flow Velocity ◽  
Artery Disease

Redistribution of Myocardial Blood Flow With Topical Nitroglycerin in Patients With Coronary Artery Disease

Circulation ◽  
1995 ◽  
Vol 91 (5) ◽  
pp. 1381-1388 ◽  
Author(s):  
Ernest L. Fallen ◽  
Claude Nahmias ◽  
Anita Scheffel ◽  
Geoff Coates ◽  
Rob Beanlands ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Blood Flow ◽  
Coronary Artery ◽  
Myocardial Blood Flow ◽  
Artery Disease ◽  
Topical Nitroglycerin

Intracoronary Doppler Assessment of Moderate Coronary Artery Disease

Circulation ◽  
1997 ◽  
Vol 96 (2) ◽  
pp. 484-490 ◽  
Author(s):  
Louis I. Heller ◽  
Christopher Cates ◽  
Jeffrey Popma ◽  
Lawrence I. Deckelbaum ◽  
James D. Joye ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Intracoronary Doppler ◽  
Artery Disease
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