ChemInform Abstract: Asymmetric Reduction of Prochiral Ketones Using in situ Generated Oxazaborolidines Derived from Amino Alcohols of (1R)-Camphor as Catalysts.

ChemInform ◽  
2001 ◽  
Vol 32 (9) ◽  
pp. no-no
Author(s):  
V. Santhi ◽  
Madhusudana J. Rao
Keyword(s):  
Asymmetric Reduction ◽  
Amino Alcohols ◽  
Prochiral Ketones

Asymmetric reduction of prochiral ketones with borane using chiral squaric amino alcohols derived from camphor as catalysts

2005 ◽  
Vol 242 (1-2) ◽  
pp. 57-61 ◽  
Author(s):  
Hai-Hua Zou ◽  
Jian Hu ◽  
Ji Zhang ◽  
Jing-Song You ◽  
Dan Ma ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Amino Alcohols ◽  
Prochiral Ketones

Syntheses of 1,2-Amino Alcohols and Their Applications for Oxazaborolidine Catalyzed Enantioselective Reduction of Aromatic Ketones

2007 ◽  
Vol 60 (3) ◽  
pp. 196 ◽  
Author(s):  
Namdev S. Vatmurge ◽  
Braja G. Hazra ◽  
Vandana S. Pore
Keyword(s):  
Amino Alcohol ◽  
Good Yield ◽  
Asymmetric Reduction ◽  
Enantiomeric Excess ◽  
Amino Alcohols ◽  
Secondary Alcohols ◽  
Aromatic Ketones ◽  
Enantioselective Reduction ◽  
Aryl Ketones

Six new chiral 1,2-amino alcohol derivatives have been synthesized starting from (1R,2R)-2-amino-1-phenylpropane-1,3-diol. Asymmetric reduction of aryl ketones with in-situ generated oxazaborolidine from these amino alcohol derivatives and BH3·Me2S afforded secondary alcohols with good yield and moderate to high enantiomeric excess.

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