ChemInform Abstract: Fragment Couplings via CO2Extrusion-Recombination: Expansion of a Classic Bond-Forming Strategy via Metallaphotoredox.

ChemInform ◽  
2016 ◽  
Vol 47 (9) ◽  
pp. no-no
Author(s):  
Chi Chip Le ◽  
David W. C. MacMillan
Keyword(s):  
Bond Forming ◽  
Forming Strategy

scholarly journals A unified synthetic strategy to introduce heteroatoms via electrochemical functionalization of alkyl organoboron reagents

2021 ◽  
Author(s):  
Hong Geun Lee ◽  
Taek Dong Chung ◽  
Su Yong Go ◽  
Hyunho Chung ◽  
Samuel Jaeho Shin ◽  
...  
Keyword(s):  
Reaction Kinetics ◽  
Steric Hindrance ◽  
Single Electron ◽  
Electrochemical Studies ◽  
Organoboron Compounds ◽  
Bond Forming ◽  
Unified Protocol ◽  
Synthetic Strategy ◽  
Forming Strategy ◽  
Reaction Profile

Based on systematic electrochemical analyses, an integrated synthetic platform of C(sp3)-based organoboron compounds was established for the introduction of heteroatoms. The electrochemically mediated bond-forming strategy was shown to be highly effective for the functionalization of sp3-hybridized carbon atoms with significant steric hindrance. Moreover, virtually all the nonmetallic heteroatoms could be utilized as reaction partners using one unified protocol. The observed reactivity stems from the two consecutive single-electron oxidations of the substrate, which eventually generates an extremely reactive carbocation as the key intermediate. The detailed reaction profile could be elucidated through multifaceted electrochemical studies and the examination of the reaction kinetics. Ultimately, a new dimension in the activation strategies for organoboron compounds was accomplished through the electrochemically driven reaction development.

scholarly journals Integrative Pericyclic Cascade: An Atom Economic, Multi C−C Bond-Forming Strategy for the Construction of Molecular Complexity

2017 ◽  
Vol 23 (42) ◽  
pp. 10048-10052 ◽  
Author(s):  
David Tejedor ◽  
Samuel Delgado-Hernández ◽  
Jesús Peyrac ◽  
Javier González-Platas ◽  
Fernando García-Tellado
Keyword(s):  
Bond Forming ◽  
Forming Strategy ◽  
Molecular Complexity

Efficient synthesis of α-(fluoro/chloro/methoxy)disulfonylmethane derivatives as tunable substituted methyl synthons via a new C–S bond forming strategy

2010 ◽  
Vol 131 (10) ◽  
pp. 1007-1012 ◽  
Author(s):  
G.K. Surya Prakash ◽  
Fang Wang ◽  
Chuanfa Ni ◽  
Tito Joe Thomas ◽  
George A. Olah
Keyword(s):  
Efficient Synthesis ◽  
Bond Forming ◽  
Forming Strategy

ChemInform Abstract: Efficient Synthesis of α-(Fluoro/chloro/methoxy)disulfonylmethane Derivatives as Tunable Substituted Methyl Synthons via a New C-S Bond Forming Strategy.

ChemInform ◽  
2011 ◽  
Vol 42 (7) ◽  
pp. no-no
Author(s):  
G. K. Surya Prakash ◽  
Fang Wang ◽  
Chuanfa Ni ◽  
Tito Joe Thomas ◽  
George A. Olah
Keyword(s):  
Efficient Synthesis ◽  
Bond Forming ◽  
Forming Strategy
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