Diagnosis of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) by fine needle aspiration cytology

2008 ◽  
Vol 36 (10) ◽  
pp. 691-695 ◽  
Author(s):  
Bipin Kumar ◽  
Smriti Karki ◽  
Punam Paudyal
2021 ◽  
Vol 7 (4) ◽  
pp. 215-218
Author(s):  
Dr. Neema Ankur Rana ◽  
◽  
Dr. Durva Vijaykumar Patel ◽  
Dr. Hiral Samir Shah ◽  
Dr. Meena Rajiv Daveshwar ◽  
...  

Rosai-Dorfman Disease (RDD) is also known as Sinus Histiocytosis of Massive Lymphadenopathy(SHML). Clinically Rosai-Dorfman Disease is characterized by massive, painless, bilateral cervicallymph node enlargement, often mimics lymphoma. Microscopically, it shows dilatation of lymphaticsinuses occupied by numerous lymphocytes and proliferation of histiocytes with abundant paleeosinophilic cytoplasm containing engulfed lymphocytes or plasma cells- emperipolesis.


2004 ◽  
Vol 31 (3) ◽  
pp. 198-199 ◽  
Author(s):  
Ram Chandra Adhikari ◽  
Gita Sayami ◽  
Min Chul Lee ◽  
Sushiela Dali ◽  
Hari Govinda Shrestha

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Meher Aziz ◽  
Prasenjit Sen Ray ◽  
Nazima Haider ◽  
Sumit Prakash Rathore

Rosai-Dorfman disease (RDD) is a rare benign disorder of histiocytic proliferation that usually presents with bilateral cervical lymphadenopathy in children. We describe the case of a 50-year-old lady suffering from this disease who presented with generalized lymphadenopathy and a left sided chest wall lump. Fine needle aspiration cytology (FNAC) from all the lesions showed abundant benign histiocytes with lymphophagocytosis which was compatible with the diagnosis of RDD. This case is being reported for its rarity in presentation in an elderly female with both generalized nodal as well as extranodal manifestations.


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