Longitudinal analysis of voice quality in patients with early glottic cancer after transoral laser microsurgery

Head & Neck ◽  
2011 ◽  
Vol 34 (9) ◽  
pp. 1294-1298 ◽  
Author(s):  
Pen-Yuan Chu ◽  
Yen-Bin Hsu ◽  
Tsung-Lun Lee ◽  
Sherry Fu ◽  
Li-Mei Wang ◽  
...  
Keyword(s):  
Longitudinal Analysis ◽  
Voice Quality ◽  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer

Effectiveness of transoral laser microsurgery for precancerous lesions and early glottic cancer guided by analysis of voice quality

Head & Neck ◽  
2013 ◽  
Vol 36 (6) ◽  
pp. 763-767 ◽  
Author(s):  
Abdulrahman Ali Bahannan ◽  
Aleš Slavíček ◽  
Libor Černý ◽  
Jan Vokřal ◽  
Zdenek Valenta ◽  
...  
Keyword(s):  
Precancerous Lesions ◽  
Voice Quality ◽  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer

Transoral laser microsurgery in early glottic cancer involving the anterior commissure

2019 ◽  
Vol 276 (3) ◽  
pp. 837-845 ◽  
Author(s):  
Christian Jacobi ◽  
Raffaela Freundorfer ◽  
Maximilian Reiter
Keyword(s):  
Anterior Commissure ◽  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer

Low expression of pRB predicts disease relapse in early glottic cancer treated with transoral laser microsurgery

2018 ◽  
Vol 129 (6) ◽  
pp. E220-E226
Author(s):  
Li‐Ang Lee ◽  
Tuan‐Jen Fang ◽  
Hsueh‐Yu Li ◽  
Chung‐Guei Huang ◽  
Tse‐Ching Chen ◽  
...  
Keyword(s):  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Disease Relapse ◽  
Laser Microsurgery ◽  
Early Glottic Cancer ◽  
Low Expression

Longitudinal analysis of Voice Handicap Index in early glottic cancer patients treated with transoral laser microsurgery: age, gender, stage and time dependence

2019 ◽  
Vol 133 (4) ◽  
pp. 318-323 ◽  
Author(s):  
C Lane ◽  
M Rigby ◽  
R Hart ◽  
J Trites ◽  
E Levi ◽  
...  
Keyword(s):  
Voice Handicap Index ◽  
Glottic Cancer ◽  
Glottic Carcinoma ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer ◽  
Related Quality ◽  
The Voice

AbstractObjectivesTransoral laser microsurgery is an increasingly common treatment modality for glottic carcinoma. This study aimed to determine the effect of age, gender, stage and time on voice-related quality of life using the Voice Handicap Index-10.MethodsPrimary early glottic carcinoma patients treated with transoral laser microsurgery were included in the study. Self-reported Voice Handicap Index testing was completed pre-operatively, three months post-operatively, and yearly at follow-up appointments.ResultsVoice Handicap Index improvement was found to be dependent on age and tumour stage, while no significant differences were found in Voice Handicap Index for gender. Voice Handicap Index score was significantly improved at 12 months and 24 months. Time versus Voice Handicap Index modelling revealed a preference for non-linear over linear regression.ConclusionAge and stage are important factors, as younger patients with more advanced tumours show greater voice improvement post-operatively. Patient's Voice Handicap Index is predicted to have 95 per cent of maximal improvement by 5.5 months post-operatively.

Repeated transoral laser microsurgery for early and advanced recurrence of early glottic cancer after primary laser resection

2010 ◽  
Vol 37 (3) ◽  
pp. 340-346 ◽  
Author(s):  
Ralph M.W. Roedel ◽  
Christoph Matthias ◽  
Hendrik A. Wolff ◽  
Hans Christiansen
Keyword(s):  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer ◽  
Laser Resection

Voice outcomes following transoral laser microsurgery for early glottic squamous cell carcinoma

2007 ◽  
Vol 121 (12) ◽  
pp. 1184-1188 ◽  
Author(s):  
J T Kennedy ◽  
P M Paddle ◽  
B J Cook ◽  
P Chapman ◽  
T A Iseli
Keyword(s):  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer ◽  
Primary Radiotherapy ◽  
Second Procedure ◽  
European Laryngological Society ◽  
Choice Of Therapy ◽  
Salvage Laryngectomy

AbstractIntroduction:Early glottic cancer may be treated with primary radiotherapy or transoral laser microsurgery with comparable survival. The choice of therapy therefore depends on patient preference after discussion of risks, benefits and alternatives.Materials and methods:All previously untreated patients undergoing transoral laser microsurgery for T1 or T2 glottic cancer at St Vincent's Hospital between July 1997 and December 2004 had their staging and demographics recorded. Surgery was categorised according to the European Laryngological Society. A voice recording was made pre-operatively then at 12 weeks post-operatively and scored by two independent speech therapists on the Oates Russell Voice Profile – a scale of zero (normal) to five (severe dysphonia). Follow up was for a minimum of two years.Results and analysis:Fifty-three patients with a mean age of 56 were included. The observed survival was T1 89.4 per cent and T2 85.3 per cent after a mean follow up of 47 months. Nineteen patients staged T1 underwent cordectomy. A second procedure was required in 22.2 per cent, however, none required a laryngectomy. Thirty-four patients staged T2 underwent hemilaryngectomy. A second procedure was required in 41.2 per cent including 8.8 per cent requiring salvage laryngectomy. One patient died with unresectable nodal disease. The mean Oates Russell Voice Profile for T1 disease was 2.37 and for T2 2.68 (range 1 to 4) indicating a mild (2) to moderate (3) degree of voice impairment.Conclusions:Survival outcomes following transoral laser microsurgery are comparable to treatment with radiotherapy. Voice impairment is usually mild to moderate following transoral laser microsurgery for early glottic cancer but overall may be greater than in radiotherapy patients. The repeatability of transoral laser microsurgery may result in a lower laryngectomy rate compared with published series using radiotherapy.

Transoral laser microsurgery for recurrence after primary radiotherapy of early glottic cancer

2010 ◽  
Vol 37 (4) ◽  
pp. 474-481 ◽  
Author(s):  
Ralph M.W. Roedel ◽  
Christoph Matthias ◽  
Hendrik A. Wolff ◽  
Phillip Schindler ◽  
Tomas Aydin ◽  
...  
Keyword(s):  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Early Glottic Cancer ◽  
Primary Radiotherapy

Transoral laser microsurgery outcomes with early glottic cancer: the Dalhousie University experience

2011 ◽  
Vol 125 (5) ◽  
pp. 509-512 ◽  
Author(s):  
S E Lester ◽  
M H Rigby ◽  
S M Taylor
Keyword(s):  
Overall Survival ◽  
Disease Free Survival ◽  
Glottic Cancer ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Free Survival ◽  
Early Glottic Cancer ◽  
Kaplan Meier ◽  
Disease Free

AbstractObjective:To report the results of transoral laser microsurgery for the treatment of early glottic cancer at our institution.Design:Cohort study. Retrospective review of charts of patients diagnosed with tumour stage 1 or 2 (early stage; no nodes or metastases), previously untreated, primary glottic cancer, treated with transoral laser microsurgery at the Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada. The minimum follow-up period was two years.Setting:Tertiary care head and neck cancer centre.Participants:Fifty-three patients treated between January 2002 and November 2007.Outcome measure:Kaplan–Meier survival analysis for disease-free survival, overall survival and laryngectomy-free survival, at five years.Results:The group comprised 46 men and seven women, with a mean age of 66 years (range 30–84 years). Mean follow up was 40 months (range 12–89 months). There were four cases of complications (7.5 per cent). Kaplan–Meier survival analysis revealed a five-year disease-free survival (including salvage) of 96.2 per cent, a five-year overall survival (all causes) of 88.8 per cent and a five-year laryngectomy-free survival of 98.1 per cent.Conclusion:Transoral laser microsurgery is a safe and effective initial treatment for early laryngeal cancer, and has high rates of laryngeal preservation and disease-free survival.

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