Clear cell variant of calcifying epithelial odontogenic tumor: Case report and review of the literature

Head & Neck ◽  
1994 ◽  
Vol 16 (3) ◽  
pp. 272-277 ◽  
Author(s):  
M. John Hicks ◽  
Catherine M. Flaitz ◽  
Mark E. K. Wong ◽  
R. Keith McDaniel ◽  
Philip T. Cagle
2009 ◽  
Vol 51 (3) ◽  
pp. 485-488 ◽  
Author(s):  
Ataollah Habibi ◽  
Nasrollah Saghravanian ◽  
Reza Zare ◽  
Hamid Jafarzadeh

2017 ◽  
Vol 25 (10) ◽  
pp. e95-e99 ◽  
Author(s):  
Braúlio C. Júnior ◽  
Vinicius R.V.M. Muniz ◽  
Manuela T.A. Vidal ◽  
Clarissa A. Gurgel ◽  
Jorge E. Leon ◽  
...  

2020 ◽  
Vol 28 (5) ◽  
pp. 526-535
Author(s):  
José Alcides Almeida de Arruda ◽  
Diego Antônio Costa Arantes ◽  
Lauren Frenzel Schuch ◽  
Carla Mosconi ◽  
Lucas Guimarães Abreu ◽  
...  

A clear cell variant of calcifying epithelial odontogenic tumor is a rare benign odontogenic neoplasm, accounting for 33 cases described in the literature. In this article, we report a challenging example of clear cell variant of calcifying epithelial odontogenic tumor of the posterior maxilla in a 45-year-old female patient showing locally aggressive growth and recurrence. Microscopically, islands of polyhedral cells containing abundant cytoplasm, well-developed intercellular bridges blended with clear cells were observed. The nuclei were frequently pleomorphic and permeated by hyaline calcified material. Immunohistochemistry revealed positivity for pan-cytokeratin (AE1/AE3), cytokeratins (CK-14 and CK-19), Bcl-2, p53, and p63. The Ki-67 proliferative index was ~10%. As odontogenic tumors are rare, when a significant clear cell component is observed, the differential diagnosis with other lesions of the jaws with similar morphology, including other odontogenic tumors with prominent clear cell component, clear cell odontogenic carcinomas, and metastatic tumors, is difficult.


Author(s):  
Márcia Gaiger de Oliveira ◽  
Anna Cecília Moraes Chaves ◽  
Fernanda Visioli ◽  
Elisabete Ulsenheimer Rojas ◽  
Sabrina Pozatti Moure ◽  
...  

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