Evaluation of deformable image registration between external beam radiotherapy and HDR brachytherapy for cervical cancer with a 3D-printed deformable pelvis phantom

2017 ◽  
Vol 44 (4) ◽  
pp. 1445-1455 ◽  
Author(s):  
Noriyuki Kadoya ◽  
Yuya Miyasaka ◽  
Yujiro Nakajima ◽  
Yoshihiro Kuroda ◽  
Kengo Ito ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
External Beam Radiotherapy ◽  
Deformable Image Registration ◽  
External Beam ◽  
Hdr Brachytherapy ◽  
3D Printed

scholarly journals Evaluation of rectum and bladder dose accumulation from external beam radiotherapy and brachytherapy for cervical cancer using two different deformable image registration techniques

2017 ◽  
Vol 58 (5) ◽  
pp. 720-728 ◽  
Author(s):  
Noriyuki Kadoya ◽  
YuYa Miyasaka ◽  
Takaya Yamamoto ◽  
Yoshihiro Kuroda ◽  
Kengo Ito ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
External Beam Radiotherapy ◽  
Deformable Image Registration ◽  
Dose Effect ◽  
Reference Image ◽  
External Beam ◽  
Similarity Coefficients ◽  
Ground Truth Data ◽  
Dose Accumulation

ABSTRACT We evaluated dose–volume histogram (DVH) parameters based on deformable image registration (DIR) between brachytherapy (BT) and external beam radiotherapy (EBRT) that included a center-shielded (CS) plan. Eleven cervical cancer patients were treated with BT, and their pelvic and CS EBRT were studied. Planning CT images for EBRT and BT (except for the first BT, used as the reference image) were deformed with DIR to reference image. We used two DIR parameter settings: intensity-based and hybrid. Mean Dice similarity coefficients (DSCs) comparing EBRT with the reference for the uterus, rectum and bladder were 0.81, 0.77 and 0.83, respectively, for hybrid DIR and 0.47, 0.37 and 0.42, respectively, for intensity-based DIR (P < 0.05). D1 cm3 for hybrid DIR, intensity-based DIR and DVH addition were 75.1, 81.2 and 78.2 Gy, respectively, for the rectum, whereas they were 93.5, 92.3 and 94.3 Gy, respectively, for the bladder. D2 cm3 for hybrid DIR, intensity-based DIR and DVH addition were 70.1, 74.0 and 71.4 Gy, respectively, for the rectum, whereas they were 85.4, 82.8 and 85.4 Gy, respectively, for the bladder. Overall, hybrid DIR obtained higher DSCs than intensity-based DIR, and there were moderate differences in DVH parameters between the two DIR methods, although the results varied among patients. DIR is only experimental, and extra care should be taken when comparing DIR-based dose values with dose–effect curves established using DVH addition. Also, a true evaluation of DIR-based dose accumulation would require ground truth data (e.g. measurement with physical phantom).

Potential Added Value of Structure-Based Deformable Image Registration for Dose Accumulation in External Beam Radiotherapy and Brachytherapy in Cervical Cancer

Brachytherapy ◽  
2016 ◽  
Vol 15 ◽  
pp. S36
Author(s):  
Laura E. van Heerden ◽  
Anette C. Houweling ◽  
Kees Koedooder ◽  
Zdenko van Kesteren ◽  
Coen R.N. Rasch ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
External Beam Radiotherapy ◽  
Deformable Image Registration ◽  
Added Value ◽  
External Beam ◽  
Dose Accumulation

Structure-based deformable image registration: Added value for dose accumulation of external beam radiotherapy and brachytherapy in cervical cancer

2017 ◽  
Vol 123 (2) ◽  
pp. 319-324 ◽  
Author(s):  
Laura E. van Heerden ◽  
Antonetta C. Houweling ◽  
Kees Koedooder ◽  
Zdenko van Kesteren ◽  
Niek van Wieringen ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
External Beam Radiotherapy ◽  
Deformable Image Registration ◽  
Added Value ◽  
External Beam ◽  
Dose Accumulation

Outcome of 6 fractions of 5.3Gray HDR brachytherapy in combination with external beam radiotherapy for treatment of cervical cancer

2013 ◽  
Vol 131 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Wee Yao Koh ◽  
Keith Lim ◽  
Jeremy Tey ◽  
Khai Mun Lee ◽  
Gek Hsiang Lim ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Hdr Brachytherapy
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