Quantitative susceptibility mapping using a superposed dipole inversion method: Application to intracranial hemorrhage

2015 ◽  
Vol 76 (3) ◽  
pp. 781-791 ◽  
Author(s):  
Hongfu Sun ◽  
Mahesh Kate ◽  
Laura C. Gioia ◽  
Derek J. Emery ◽  
Kenneth Butcher ◽  
...  

Author(s):  
Yan Wen ◽  
Pascal Spincemaille ◽  
Thanh Nguyen ◽  
Junghun Cho ◽  
Ilhami Kovanlikaya ◽  
...  


2015 ◽  
Vol 36 (8) ◽  
pp. 1424-1433 ◽  
Author(s):  
Kohsuke Kudo ◽  
Tian Liu ◽  
Toshiyuki Murakami ◽  
Jonathan Goodwin ◽  
Ikuko Uwano ◽  
...  

The purposes of this study are to establish oxygen extraction fraction (OEF) measurements using quantitative susceptibility mapping (QSM) of magnetic resonance imaging (MRI), and to compare QSM–OEF data with the gold standard 15O positron emission tomography (PET). Twenty-six patients with chronic unilateral internal carotid artery or middle cerebral artery stenosis or occlusion, and 15 normal subjects were included. MRI scans were conducted using a 3.0 Tesla scanner with a three-dimensional spoiled gradient recalled sequence. QSM images were created using the morphology-enabled dipole inversion method, and OEF maps were generated from QSM images using extraction of venous susceptibility induced by deoxygenated hemoglobin. Significant correlation of relative OEF ratio to contra-lateral hemisphere between QSM–OEF and PET–OEF was observed (r = 0.62, p < 0.001). The local (intra-section) correlation was also significant (r = 0.52, p < 0.001) in patients with increased PET–OEF. The sensitivity and specificity of OEF increase in QSM was 0.63 (5/8) and 0.89 (16/18), respectively, in comparison with PET. In conclusion, good correlation was achieved between QSM–OEF and PET–OEF in the identification of elevated OEF in affected hemispheres of patients with unilateral chronic steno-occlusive disease.



NeuroImage ◽  
2018 ◽  
Vol 179 ◽  
pp. 166-175 ◽  
Author(s):  
Hongfu Sun ◽  
Yuhan Ma ◽  
M. Ethan MacDonald ◽  
G. Bruce Pike


Radiology ◽  
2018 ◽  
Vol 288 (3) ◽  
pp. 830-839 ◽  
Author(s):  
Hongfu Sun ◽  
Ana C. Klahr ◽  
Mahesh Kate ◽  
Laura C. Gioia ◽  
Derek J. Emery ◽  
...  


Author(s):  
Aleksandra Gozt ◽  
Sarah Hellewell ◽  
Phillip GD Ward ◽  
Michael Bynevelt ◽  
Melinda Fitzgerald


2020 ◽  
Author(s):  
Yang Gao ◽  
Xuanyu Zhu ◽  
Bradford A. Moffat ◽  
Rebecca Glarin ◽  
Alan H. Wilman ◽  
...  


NeuroImage ◽  
2016 ◽  
Vol 125 ◽  
pp. 1131-1141 ◽  
Author(s):  
Berkin Bilgic ◽  
Luke Xie ◽  
Russell Dibb ◽  
Christian Langkammer ◽  
Aysegul Mutluay ◽  
...  


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