Pulmonary vascular disease in ventricular septal defect: Structural and functional correlations in lung biopsies from 85 patients, with outcome of intra-cardiac repair

1987 ◽  
Vol 152 (3) ◽  
pp. 157-168 ◽  
Author(s):  
Sheila G. Haworth
Keyword(s):  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Septal Defect ◽  
Cardiac Repair ◽  
Pulmonary Vascular Disease ◽  
Lung Biopsies

Operable ventricular septal defect despite severe pulmonary hypertension and cyanosis!

2019 ◽  
Vol 29 (7) ◽  
pp. 986-988
Author(s):  
Shyam S. Kothari ◽  
Jay Relan ◽  
Velayoudam Devagourou
Keyword(s):  
Pulmonary Hypertension ◽  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Mitral Stenosis ◽  
Septal Defect ◽  
The Other ◽  
Pulmonary Vascular Disease ◽  
Early Age ◽  
Eisenmenger Syndrome ◽  
Severe Pulmonary Hypertension

AbstractPatients with a significant left-to-right shunt at ventricular level may become inoperable at an early age due to irreversible pulmonary vascular disease. On the other hand, even suprasystemic pulmonary hypertension due to mitral stenosis remains treatable. We report a 24-year-old patient with large ventricular septal defect, severe mitral stenosis and cyanosis who improved after surgical correction of both the lesions. This emphasises the importance of additional post-capillary pulmonary hypertension in Eisenmenger syndrome.

INCREASING PULMONARY VASCULAR RESISTANCE DURING INFANCY IN ASSOCIATION WITH VENTRICULAR SEPTAL DEFECT

PEDIATRICS ◽  
1966 ◽  
Vol 38 (2) ◽  
pp. 220-230 ◽  
Author(s):  
Julien I. E. Hoffman ◽  
Abraham M. Rudolph
Keyword(s):  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Pulmonary Vascular Resistance ◽  
Vascular Resistance ◽  
Septal Defect ◽  
The Other ◽  
Pulmonary Vascular Disease ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Pulmonary Arterial

Three children with big ventricular septal defects, large pulmonary blood flows, and pulmonary hypertension were catheterized at the ages of 3, 6, and 6 months. Pulmonary vascular resistance was low in two and slightly raised in the other. Recatheterization at the ages of 9, 16, and 26 months, respectively, showed increases of pulmonary vascular resistance in all, and the ventricular septal defects were successfully closed by open-heart operation soon thereafter. In the one child who was recatheterized only after there was clinical evidence of a raised pulmonary vascular resistance, postoperative catheterization showed a progressive rise in pulmonary vascular resistance indicating progressive pulmonary vascular disease. The other two children who were clinically well were recatheterized specifically to try and detect early pulmonary vascular changes and, in contrast, in both of these children pulmonary arterial pressures and vascular resistances have returned to normal after operation. These patients demonstrate that in those at risk of developing pulmonary vascular disease (big ventricular septal defect with high pressures and flows), pulmonary vascular resistance can rise rapidly in early life. In these patients progressive pulmonary vascular disease could be prevented if surgery to lower pulmonary arterial pressure and blood flow is done early enough. Even in patients who appear to be improving, recatheterization is necessary to demonstrate a moderate rise in pulmonary vascular resistance, since a moderate rise is not detectable by current clinical techniques.

Palliative arterial repair for transposition, ventricular septal defect, and pulmonary vascular disease

1992 ◽  
Vol 54 (2) ◽  
pp. 355-356 ◽  
Author(s):  
Ara K. Pridjian ◽  
Theresa A. Tacy ◽  
Douglas Teske ◽  
Edward L. Bove
Keyword(s):  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Septal Defect ◽  
Pulmonary Vascular Disease ◽  
Arterial Repair

DIAGNOSIS AND TREATMENT: MANAGEMENT OF VENTRICULAR SEPTAL DEFECT

PEDIATRICS ◽  
1964 ◽  
Vol 34 (2) ◽  
pp. 271-273
Author(s):  
Alexander S. Nadas
Keyword(s):  
Blood Flow ◽  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Pulmonary Blood Flow ◽  
Septal Defect ◽  
Pulmonary Vasculature ◽  
Pulmonary Vascular Disease ◽  
The Status ◽  
Full Analysis ◽  
Intelligent Management

Intelligent management of a ventricular septal defect necessitates full analysis of the size of the defect, the shunt across it and the status of the pulmonary vasculature. Only patients with moderate or large defects with appreciably increased pulmonary blood flow deserve surgery. Those with small left-to-right shunts, with or without pulmonary vascular disease, should be managed medically.

scholarly journals CARDIOGRAPHIC ASSESSMENT OF PULMONARY VASCULAR DISEASE IN VENTRICULAR SEPTAL DEFECT

Heart ◽  
1962 ◽  
Vol 24 (5) ◽  
pp. 529-541 ◽  
Author(s):  
A. Hollman ◽  
J. F. Goodwin ◽  
L. Basta
Keyword(s):  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Septal Defect ◽  
Pulmonary Vascular Disease
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