Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12456 ◽

2019 ◽

Vol 8 (11) ◽

pp. 835-844 ◽

Author(s):

Paul R. V. Malik ◽

Andrea N. Edginton

Keyword(s):

Allometric Scaling ◽

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically based pharmacokinetic modeling of candesartan related to CYP2C9 genetic polymorphism in adult and pediatric patients

Archives of Pharmacal Research ◽

10.1007/s12272-021-01363-1 ◽

2021 ◽

Author(s):

Eui Hyun Jung ◽

Chang-Keun Cho ◽

Pureum Kang ◽

Hye-Jung Park ◽

Yun Jeong Lee ◽

...

Keyword(s):

Genetic Polymorphism ◽

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2003.07.004 ◽

2003 ◽

Vol 38 (3) ◽

pp. 345-367 ◽

Author(s):

C.R Kirman ◽

L.M Sweeney ◽

M.E Meek ◽

M.L Gargas

Keyword(s):

Allometric Scaling ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Dose Dependency ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling to Supplement Nilotinib Pharmacokinetics and Confirm Dose Selection in Pediatric Patients

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2019.01.028 ◽

2019 ◽

Vol 108 (6) ◽

pp. 2191-2198 ◽

Author(s):

Tycho Heimbach ◽

Wen Lin ◽

Florence Hourcade-Potelleret ◽

Xianbin Tian ◽

Francois Pierre Combes ◽

...

Keyword(s):

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Dose Selection ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Dosage Adjustment for Ceftazidime in Pediatric Patients With Renal Impairment Using Physiologically Based Pharmacokinetic Modeling

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.02.001 ◽

2021 ◽

Author(s):

Jie Zhou ◽

Xiang You ◽

Meng Ke ◽

Lingling Ye ◽

Wanhong Wu ◽

...

Keyword(s):

Renal Impairment ◽

Pediatric Patients ◽

Dosage Adjustment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Prediction of Clearance in Neonates and Infants (≤ 3 Months of Age) for Drugs That Are Glucuronidated: A Comparative Study Between Allometric Scaling and Physiologically Based Pharmacokinetic Modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.837 ◽

2016 ◽

Vol 57 (4) ◽

pp. 476-483 ◽

Author(s):

Iftekhar Mahmood ◽

Tasneem Ahmad ◽

Najia Mansoor ◽

S. M. Sharib

Keyword(s):

Comparative Study ◽

Allometric Scaling ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Neonates And Infants

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A Comparative Study Between Allometric Scaling and Physiologically Based Pharmacokinetic Modeling for the Prediction of Drug Clearance From Neonates to Adolescents

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1310 ◽

2018 ◽

Vol 59 (2) ◽

pp. 189-197 ◽

Author(s):

Iftekhar Mahmood ◽

Million A. Tegenge

Keyword(s):

Comparative Study ◽

Allometric Scaling ◽

Drug Clearance ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling and Allometric Scaling in Pediatric Drug Development: Where Do We Draw the Line?

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1834 ◽

2021 ◽

Vol 61 (S1) ◽

Author(s):

Trevor N. Johnson ◽

Alice B. Ke

Keyword(s):

Drug Development ◽

Allometric Scaling ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Pediatric Drug ◽

Pediatric Drug Development ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Ceftaroline Dosage Optimized for Pediatric Patients with Renal Impairment Using Physiologically Based Pharmacokinetic Modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1944 ◽

2021 ◽

Author(s):

Jie Zhou ◽

Xiang You ◽

Guimu Guo ◽

Meng Ke ◽

Jianwen Xu ◽

...

Keyword(s):

Renal Impairment ◽

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Modeling of Remdesivir and its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients with COVID‐19

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2176 ◽

2021 ◽

Author(s):

Justin D. Lutz ◽

Anita Mathias ◽

Polina German ◽

Cheryl Pikora ◽

Sunila Reddy ◽

...

Keyword(s):

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Dose Selection ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Physiologically Based Pharmacokinetic Modeling and Dose Adjustment of Teicoplanin in Pediatric Patients with Renal Impairment

The Journal of Clinical Pharmacology ◽

10.1002/jcph.2000 ◽

2021 ◽

Author(s):

Jianwen Xu ◽

Rongfang Lin ◽

Yong Chen ◽

Xiang You ◽

Pinfang Huang ◽

...

Keyword(s):

Renal Impairment ◽

Dose Adjustment ◽

Pediatric Patients ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text