Control charts serve as an effective tool for controlling and monitoring process quality in industries of production and service. The Shewhart chart is the first control chart that was used to detect large mean shifts in a process. Since then, to increase the Shewhart chart’s sensitivity, synthetic type control charts, such as synthetic control chart, side sensitive group runs (SSGR) control chart, have been proposed. SSGR chart ismore efficient compared to the Shewhart chart and synthetic chart,primarily due to the side sensitive feature in SSGR chart. Meanwhile, exponentially weighted moving average (EWMA) chart isoften used to detect small process changes. In practice, the evaluation of a control chart’s performance is vital. Nevertheless, the cost of implementing a control chart is an important factor that influences the choice of a control chart. The cost of repairs, sampling, nonconforming products from a failure in detecting out-of-control status, and investigating false alarms, can be significantly high. Therefore, the aim of this paper is to compare the implementation cost of synthetic, SSGR and EWMA charts, so that quality practitioners can identify the most cost-effective chart to implement. Here, the cost function was adopted to compute the implementation cost of the control chart. According to the findings, quality practitioners are recommended to adopt the SSGR chart,since it is more economical compared to the synthetic chart. However, the cost to implement anEWMA chart is higher than the synthetic and SSGR charts. In light of this, this study allows for quality practitioners to have a better idea on the selection of the control chart to implement, with respect to its cost.