Inhibitory Effect of a Thromboxane A2 Synthetase Inhibitor OKY-046 on Bronchial Hyperresponsiveness to Histamine, but not on Airway Wall Thickening, Induced by Intravenous Administration of Leukotriene C4 in Guinea-pigs

Guinea Pigs ◽

Bronchial Hyperresponsiveness ◽

Thromboxane A2 ◽

Inhibitory Effect ◽

Wall Thickening ◽

Leukotriene C4 ◽

Airway Wall ◽

Synthetase Inhibitor ◽

Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs

Clinical & Experimental Allergy ◽

10.1111/j.1365-2222.1993.tb00262.x ◽

1993 ◽

Vol 23 (10) ◽

pp. 843-850 ◽

Cited By ~ 3

Author(s):

M. KUROSAWA ◽

S. YODONAWA ◽

H. TSUKAGOSHI

Keyword(s):

Guinea Pigs ◽

Bronchial Hyperresponsiveness ◽

Thromboxane A2 ◽

Leukotriene C4 ◽

Receptor Antagonists ◽

Thromboxane A2 Receptor

Inhibitory Effect of CV4151, a Thromboxane A2 Synthetase Inhibitor, on Ventricular Arrhythmias Induced by Coronary Artery Occlusion in Rats

Japanese Circulation Journal ◽

10.1253/jcj.60.349 ◽

1996 ◽

Vol 60 (6) ◽

pp. 349-354 ◽

Cited By ~ 3

Author(s):

Ken Umetani ◽

Kohji Tamura ◽

Sadayoshi Komori ◽

Akinori Watanabe ◽

Tukasa Ishihara ◽

...

Keyword(s):

Coronary Artery ◽

Ventricular Arrhythmias ◽

Thromboxane A2 ◽

Coronary Artery Occlusion ◽

Inhibitory Effect ◽

Artery Occlusion ◽

Synthetase Inhibitor ◽

Effect of a thromboxane A2 synthetase inhibitor (OKY-046 · HCl) on airway hyperresponsiveness in guinea pigs

European Journal of Pharmacology ◽

10.1016/0014-2999(90)90669-w ◽

1990 ◽

Vol 184 (1) ◽

pp. 87-95 ◽

Cited By ~ 19

Author(s):

Hidetada Komatsu ◽

Yasuo Takehana ◽

Shinji Kikuchi ◽

Masami Kojima ◽

Shuichiro Hamano ◽

...

Keyword(s):

Guinea Pigs ◽

Airway Hyperresponsiveness ◽

Thromboxane A2 ◽

Synthetase Inhibitor ◽

Effects of Y-20811, a specific thromboxane A2 synthetase inhibitor, on chemical mediator-induced bronchoconstriction in guinea pigs.

Folia Pharmacologica Japonica ◽

10.1254/fpj.97.5_277 ◽

1991 ◽

Vol 97 (5) ◽

pp. 277-286

Author(s):

Masahiko KAGOSHIMA ◽

Noriko TOMOMATSU ◽

Tetsuko FUKUDA ◽

Hiroshi MIKASHIMA ◽

Michio TERASAWA

Keyword(s):

Guinea Pigs ◽

Thromboxane A2 ◽

Chemical Mediator ◽

Synthetase Inhibitor ◽

Effect of OKY-046, a new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs

Prostaglandins Leukotrienes and Medicine ◽

10.1016/0262-1746(87)90141-7 ◽

1987 ◽

Vol 30 (2-3) ◽

pp. 111-121 ◽

Cited By ~ 16

Author(s):

Hiroichi Nagai ◽

Ikuhisa Yakuo ◽

Michinori Togawa ◽

Akinori Arimura ◽

Naosuke Matsuura ◽

...

Keyword(s):

Guinea Pigs ◽

Thromboxane A2 ◽

Synthetase Inhibitor ◽

Bronchial hyperresponsiveness to histamine induced by intravenous administration of thromboxane A2 (TXA2) and prostaglandin D2 (PGD2) in guinea-pigs.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)38376-3 ◽

1991 ◽

Vol 55 ◽

pp. 122

Author(s):

HIDEO TSURAGOSHI ◽

MOTOHIRO KUROSAWA

Keyword(s):

Guinea Pigs ◽

Bronchial Hyperresponsiveness ◽

Thromboxane A2 ◽

Prostaglandin D2

Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs

Clinical & Experimental Allergy ◽

10.1111/j.1365-2222.1994.tb02729.x ◽

1994 ◽

Vol 24 (10) ◽

pp. 960-968 ◽

Cited By ~ 13

Author(s):

M. KUROSAWA ◽

S. YODONAWA ◽

H. TSUKAGOSHI ◽

Y. MIYACHI

Keyword(s):

Receptor Antagonist ◽

Guinea Pigs ◽

Airway Hyperresponsiveness ◽

Wall Thickening ◽

Leukotriene C4 ◽

Airway Wall ◽

Leukotriene Receptor Antagonist ◽

Leukotriene D4 ◽

Leukotriene Receptor

Effect of Y-20811, a potent and new thromboxane A2 synthetase inhibitor, on experimental asthma in guinea pigs and rats

European Journal of Pharmacology ◽

10.1016/0014-2999(90)93064-w ◽

1990 ◽

Vol 183 (2) ◽

pp. 224-225 ◽

Cited By ~ 1

Author(s):

H. Mikashima ◽

M. Terasawa ◽

N. Tomomatsu ◽

M. Setoguchi ◽

T. Tahara

Keyword(s):

Guinea Pigs ◽

Thromboxane A2 ◽

Synthetase Inhibitor ◽

Inhibitory Effect of Thromboxane A2 Synthetase Inhibitor, DP-1904, on Antigen-Induced Contraction of Human Lung Parenchyma

Annals of Allergy Asthma & Immunology ◽

10.1016/s1081-1206(10)63355-8 ◽

1996 ◽

Vol 77 (6) ◽

pp. 483-487 ◽

Cited By ~ 3

Author(s):

Chizu Fukushima ◽

Terufumi Shimoda ◽

Hiroto Matsuse ◽

Atsuko Takao ◽

Hiroyuki Sakai ◽

...

Keyword(s):

Human Lung ◽

Thromboxane A2 ◽

Lung Parenchyma ◽

Inhibitory Effect ◽

Synthetase Inhibitor ◽

CV6209 inhibits airway wall thickening and airway hyperresponsiveness to histamine induced by intravenous administration of platelet-activating factor in guinea pigs

Journal of Lipid Mediators and Cell Signalling ◽

10.1016/0929-7855(95)00057-7 ◽

1996 ◽

Vol 13 (2) ◽

pp. 139-149 ◽

Cited By ~ 1

Author(s):

Motohiro Kurosawa ◽

Hideo Tsukagoshi ◽

Yasushi Igarashi ◽

Yoshiki Miyachi

Keyword(s):

Guinea Pigs ◽

Airway Hyperresponsiveness ◽

Platelet Activating Factor ◽

Wall Thickening ◽

Airway Wall