Hypotheses concerning the mechanism of action of antidepressant drugs

Author(s):  
Jerzy Maj ◽  
Edmund Przegalinski ◽  
Ewa Mogilnicka
Cephalalgia ◽  
1985 ◽  
Vol 5 (2_suppl) ◽  
pp. 225-228 ◽  
Author(s):  
N Martucci ◽  
V Manna ◽  
A Agnoli

There is evidence that some antidepressant drugs, above all amitriptyline and mianserine, are beneficial in the prophylaxis of migraine. The mechanism of action of antidepressants in migraine is likely to be complex. Mood disturbances accompanying migraine syndromes suggest a mode of action of such a class of drugs. In the last few years some clinical studies tend to show that the antimigraine effects of these drugs seem relatively independent of the antidepressant activity.


Depression ◽  
1994 ◽  
Vol 2 (3) ◽  
pp. 119-126 ◽  
Author(s):  
Nicoletta Brunello ◽  
Salomon Z. Langer ◽  
Jorge Perez ◽  
Giorgio Racagni

2006 ◽  
Vol 107 (3) ◽  
pp. 1139-1146 ◽  
Author(s):  
L. G. Abood ◽  
H. Kimizuka ◽  
G. Rogeness ◽  
J. H. Biel

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