Morphologic Study of Glucagon Release

Author(s):  
J.-L. Carpentier ◽  
F. Malaisse-Lagae ◽  
W. Müller ◽  
L. Orci
Author(s):  
Evgeny Shaydakov ◽  
Vladimir Sannikov ◽  
Vladimir Emelynenko ◽  
Tatyana Tolstikova
Keyword(s):  

1977 ◽  
Vol 14 (2) ◽  
pp. 121-127 ◽  
Author(s):  
R. Müller-Peddinghaus ◽  
G. Trautwein

A morphologic study of 103 dogs, including two with renal amyloidosis, showed that different types of diffuse glomerulonephritis are correlated with different age groups. Membranous and membranoproliferative glomerulonephritis were more common in middle-aged and older animals, whereas mesangial lesions were found predominantly in younger dogs and considered to be early glomerular changes. Glomerulonephritis largely occurred independently of interstitial nephritis. The incidence of interstitial lesions was 71%. Chronic interstitial nephritis was rare in dogs under 1 year old. Glomerulonephritis did not seem to induce interstitial nephritis. Glomerulonephritis occurred not only in kidneys with severe interstitial damage, but also in those with slight damage. This indicated that glomerulonephritis occurred independently of interstitial nephritis. In end-stage kidneys with severe fibrosis, mesangial changes seemed to predominate.


1997 ◽  
Vol 19 (4) ◽  
pp. 249-255
Author(s):  
R. Wolfram-Gabel ◽  
J. L. Kahn ◽  
P. Bourjat
Keyword(s):  

1966 ◽  
Vol 124 (2) ◽  
pp. 199-208 ◽  
Author(s):  
Jadwiga Koziorowska ◽  
Krzysztof Włodarski

A morphologic study has been made on KB cells infected with various doses of vaccinia as to DNA synthesis and mitosis. Determination of mitotic indices revealed that the mitotic cell pool depended on the proportion of infected cells and the time after infection. By cytologic examination neither mitotic lesions were found nor an accumulation of mitotic cells at any one stage of mitosis was demonstrated. Radioautographs of infected cultures have shown that the frequency of cells labeled over nuclei was significantly increased as compared with control cultures. Following the greatest dose of virus (multiplicity of 20 PFU/cell) the ratio of cells synthesizing DNA to mitotic cells increased from 45:5 at 5 hr to 50:0 at 50 hr. Concommittant with the appearance of this disparity between the DNA-synthesizing cell pool and mitotic cell pool the nuclei of cells became "lightly" labeled. Following the lowest dose of virus (multiplicity of 0.0002 PFU/cell) the increase of the fraction of mitotic cells was proportional to the increase of the fraction of cells which were labeled over nuclei.


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