Increased Dietary Calcium Intake Reduces Urinary Oxalate Excretion in Healthy Adults

Urolithiasis ◽  
1989 ◽  
pp. 435-438 ◽  
Author(s):  
J. Lemann ◽  
J. A. Pleuss ◽  
R. W. Gray
1996 ◽  
Vol 49 (1) ◽  
pp. 200-208 ◽  
Author(s):  
Jacob Lemann ◽  
Joan A. Pleuss ◽  
Elaine M. Worcester ◽  
Laurel Hornick ◽  
Debra Schrab ◽  
...  

1998 ◽  
Vol 159 (2S) ◽  
pp. 615-616
Author(s):  
J. Lemann ◽  
J.A. Pleuss ◽  
E.M. Worcester ◽  
L. Hornick ◽  
D. Schrab ◽  
...  

2002 ◽  
Vol 35 (6) ◽  
pp. 669-675 ◽  
Author(s):  
J.L. Nishiura ◽  
L.A. Martini ◽  
C.O.G. Mendonça ◽  
N. Schor ◽  
I.P. Heilberg

2011 ◽  
Vol 186 (1) ◽  
pp. 135-139 ◽  
Author(s):  
Juquan Jiang ◽  
John Knight ◽  
Linda H. Easter ◽  
Rebecca Neiberg ◽  
Ross P. Holmes ◽  
...  

Author(s):  
J M Brown ◽  
G Stratmann ◽  
D M Cowley ◽  
B M Mottram ◽  
A H Chalmers

Twenty-two recurrent calcium stone formers had 24-h urinary oxalate excretions on their home diets which were significantly greater than those of 30 normal subjects (0·48±0·23 mmol/d; mean±SD compared with 0·31±0·11; P<0·01). The stone formers also demonstrated marked day to day variability in oxalate excretion indicating that a single normal urinary oxalate measurement did not exclude significant hyperoxaluria at other times. On a hospital diet containing 1000 mg calcium per day, urinary oxalate excretion fell significantly from 0·48±0·23 mmol/d to 0·32±0·12; P<0·01. As the urinary calcium excretion in and out of hospital was similar, it seems unlikely that low calcium intake at home was responsible for the hyperoxaluria. All patients had recurrent symptomatic stone disease and had been advised to avoid foods rich in oxalate. Whilst poor compliance is a possible explanation for the variability in oxalate excretion, we believe it is more likely that there is an inadvertent intake of oxalogenic precursors in their diet. As normal subjects do not demonstrate hyperoxaluria on similar home diets, stone formers may have a metabolic defect in the handling of these precursors.


2014 ◽  
Vol 84 (3-4) ◽  
pp. 0206-0217 ◽  
Author(s):  
Seyedeh-Elaheh Shariati-Bafghi ◽  
Elaheh Nosrat-Mirshekarlou ◽  
Mohsen Karamati ◽  
Bahram Rashidkhani

Findings of studies on the link between dietary acid-base balance and bone mass are relatively mixed. We examined the association between dietary acid-base balance and bone mineral density (BMD) in a sample of Iranian women, hypothesizing that a higher dietary acidity would be inversely associated with BMD, even when dietary calcium intake is adequate. In this cross-sectional study, lumbar spine and femoral neck BMDs of 151 postmenopausal women aged 50 - 85 years were measured using dual-energy x-ray absorptiometry. Dietary intakes were assessed using a validated food frequency questionnaire. Renal net acid excretion (RNAE), an estimate of acid-base balance, was then calculated indirectly from the diet using the formulae of Remer (based on dietary intakes of protein, phosphorus, potassium, and magnesium; RNAERemer) and Frassetto (based on dietary intakes of protein and potassium; RNAEFrassetto), and was energy adjusted by the residual method. After adjusting for potential confounders, multivariable adjusted means of the lumbar spine BMD of women in the highest tertiles of RNAERemer and RNAEFrassetto were significantly lower than those in the lowest tertiles (for RNAERemer: mean difference -0.084 g/cm2; P=0.007 and for RNAEFrassetto: mean difference - 0.088 g/cm2; P=0.004). Similar results were observed in a subgroup analysis of subjects with dietary calcium intake of >800 mg/day. In conclusion, a higher RNAE (i. e. more dietary acidity), which is associated with greater intake of acid-generating foods and lower intake of alkali-generating foods, may be involved in deteriorating the bone health of postmenopausal Iranian women, even in the context of adequate dietary calcium intake.


Sign in / Sign up

Export Citation Format

Share Document