Reconstruction of the Pelvis After Resection of Malignant Bone Tumours in Children and Adolescents

2009 ◽  
pp. 85-111 ◽  
Author(s):  
Martin Dominkus ◽  
Eslam Darwish ◽  
Philipp Funovics
Keyword(s):  
Children And Adolescents ◽  
Bone Tumours ◽  
Malignant Bone Tumours

scholarly journals Primary malignant bone tumours of spine and pelvis in children

2021 ◽  
Vol 15 (4) ◽  
pp. 337-345
Author(s):  
Ilkka J. Helenius ◽  
Andreas H. Krieg
Keyword(s):  
Children And Adolescents ◽  
Axial Skeleton ◽  
Bone Tumours ◽  
En Bloc ◽  
Scientific Publications ◽  
Level Of Evidence ◽  
Spinal Reconstruction ◽  
Malignant Bone Tumours ◽  
En Bloc Excision ◽  
Bloc Excision

Purpose Axial malignant bone tumours are rare in children and adolescents, and their prognosis is still relatively poor due to non-specific symptoms, such as back or groin pain, which may result in late hospital presentation. Therefore, it is very important to raise awareness regarding this pathology. Methods We performed a narrative review, including scientific publications published in English. We searched Medline and Google Scholar databases for information on the incidence and prognosis of axial malignant bone tumours in children and adolescents (< 18 years). Outcomes of different surgical management strategies and reconstruction options were assessed. Results The incidence of primary malignant bone tumours before the age of 18 years is approximately five per one million population; around 25% of these tumours are located in the axial skeleton. With a five-year survival rate of 50%, tumours in an axial location (chest cage, spine, pelvis) are associated with a poorer prognosis than tumours in more peripheral locations. En bloc excision with clear margins has been shown to improve local control and overall survival, even though obtaining adequate surgical margins is difficult due to the close location of large neurovascular structures and other major organs. Spinal reconstruction options include instrumented fusion with allograft or expandable cage. Pelvic reconstruction is needed in internal hemipelvectomy, and the options include biological, endoprosthetic reconstructions, hip transposition, arthrodesis or creation of pseudoarthrosis and lumbopelvic instrumentation. Conclusion Early diagnosis, a timely adequate multidisciplinary management, appropriate en bloc excision, and reconstruction improve survival and quality of life in these patients. Level of Evidence V

scholarly journals Treatment of primary malignant bone tumours of the distal tibia

2005 ◽  
Vol 29 (4) ◽  
pp. 255-259 ◽  
Author(s):  
M. Laitinen ◽  
J. Hardes ◽  
H. Ahrens ◽  
C. Gebert ◽  
B. Leidinger ◽  
...  
Keyword(s):  
Distal Tibia ◽  
Bone Tumours ◽  
Malignant Bone Tumours

The course of fibrinolytic proteins in children with malignant bone tumours

1999 ◽  
Vol 158 (S3) ◽  
pp. S151-S153 ◽  
Author(s):  
U. Nowak-Göttl ◽  
N. Münchow ◽  
U. Klippel ◽  
M. Paulussen ◽  
S. Bielack ◽  
...  
Keyword(s):  
Bone Tumours ◽  
Malignant Bone Tumours ◽  
Fibrinolytic Proteins

scholarly journals Treatment of malignant bone tumours by extracorporeally irradiated autograft-prosthetic composite arthroplasty

2002 ◽  
Vol 84-B (8) ◽  
pp. 1156-1161 ◽  
Author(s):  
W. M. Chen ◽  
T. H. Chen ◽  
C. K. Huang ◽  
C. C. Chiang ◽  
W. H. Lo
Keyword(s):  
Bone Tumours ◽  
Malignant Bone Tumours

Imaging following allograft reconstruction in children with malignant bone tumours

1999 ◽  
Vol 29 (10) ◽  
pp. 785-793 ◽  
Author(s):  
D. J. Roebuck ◽  
James F. Griffith ◽  
Shekar M. Kumta ◽  
P. C. Leung ◽  
Constantine Metreweli
Keyword(s):  
Bone Tumours ◽  
Allograft Reconstruction ◽  
Malignant Bone Tumours

Role of Trauma in the Development of Malignant Bone Tumours

1963 ◽  
Vol 1 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Carl Krebs ◽  
Kaj Olsen
Keyword(s):  
Bone Tumours ◽  
Malignant Bone Tumours

Bone cancer

2020 ◽  
pp. 4709-4713
Author(s):  
Helen Hatcher
Keyword(s):  
Metastatic Disease ◽  
Ewing Sarcoma ◽  
Bone Biopsy ◽  
Tumour Size ◽  
External Beam Radiotherapy ◽  
Bone Tumours ◽  
Malignant Bone Tumours ◽  
Primary Bone ◽  
Bony Metastases ◽  
Primary Bone Tumours

Benign bone tumours are common, usually asymptomatic, and discovered incidentally. Malignant primary bone tumours are uncommon but cause significant morbidity and mortality, particularly in adolescents and young adults. Bony metastases are the tumours most frequently seen in bone. Malignant bone tumours typically present with localized pain or swelling. With patients in whom the diagnosis is not clearly metastatic disease, determination of tumour size and extent is best achieved by magnetic resonance imaging, and bone biopsy is mandatory to establish a precise histological diagnosis. Osteosarcoma, chondrosarcoma, and Ewing sarcoma are the three commonest primary bone tumours. In determining management, the main clinical distinction is between localized and metastatic disease. Non-metastatic primary tumours are treated with surgery (when possible) and chemotherapy (osteosarcoma and Ewing sarcoma, sometimes chondrosarcoma). Symptomatic bony metastases are usually treated with external beam radiotherapy.

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