The Plant Mitochondrial Transfer RNAs Have Three Different Genetic Origins

1994 ◽  
pp. 333-345 ◽  
Author(s):  
André Dietrich ◽  
Laurence Maréchal-Drouard ◽  
Jacques-Henry Weil
Keyword(s):  
Transfer Rnas ◽  
Mitochondrial Transfer ◽  
Genetic Origins

scholarly journals Transfer RNAs of potato (Solanum tuberosum) mitochondria have different genetic origins

1990 ◽  
Vol 18 (13) ◽  
pp. 3689-3696 ◽  
Author(s):  
Laurence Marechal-Drouard ◽  
Pierre Guillemaut ◽  
Anne Cosset ◽  
Michèle Arbogast ◽  
Frédérique Weber ◽  
...  
Keyword(s):  
Solanum Tuberosum ◽  
Transfer Rnas ◽  
Genetic Origins

Import and editing of plant mitochondrial transfer RNAs

1998 ◽  
pp. 113-124
Author(s):  
Laurence Maréchal-Drouard ◽  
Ian Small ◽  
Anne Cosset ◽  
Anne-Marie Duchêne ◽  
Raman Kumar ◽  
...  
Keyword(s):  
Transfer Rnas ◽  
Mitochondrial Transfer

scholarly journals A comprehensive collection of annotations to interpret sequence variation in human mitochondrial transfer RNAs

2016 ◽  
Vol 17 (S12) ◽  
Author(s):  
Maria Angela Diroma ◽  
Paolo Lubisco ◽  
Marcella Attimonelli
Keyword(s):  
Sequence Variation ◽  
Transfer Rnas ◽  
Comprehensive Collection ◽  
Mitochondrial Transfer

scholarly journals Mammalian mitochondrial transfer RNAs: chromatographic properties, size and origin

1979 ◽  
Vol 6 (2) ◽  
pp. 455-469 ◽  
Author(s):  
Luke Aujame ◽  
Karl B. Freeman
Keyword(s):  
Transfer Rnas ◽  
Mitochondrial Transfer

Tumor mitochondrial transfer RNAS: The nucleotide sequence of mitochondrial tRNALeuUAG from morris hepatoma 5123D

1981 ◽  
Vol 100 (2) ◽  
pp. 732-737 ◽  
Author(s):  
Kurt Randerath ◽  
Hari P. Agrawal ◽  
Erika Randerath
Keyword(s):  
Nucleotide Sequence ◽  
Transfer Rnas ◽  
Mitochondrial Transfer ◽  
Morris Hepatoma

Mosquito mitochondrial transfer RNAs for valine, glycine and glutamate: RNA and gene sequences and vicinal genome organization 19851230

1986 ◽  
Vol 10 (9) ◽  
pp. 701-707 ◽  
Author(s):  
Donald T. Dubin ◽  
Chuen-Chin HsuChen ◽  
Lucia E. Tillotson
Keyword(s):  
Genome Organization ◽  
Gene Sequences ◽  
Transfer Rnas ◽  
Mitochondrial Transfer

Mitochondrial transfer RNAs in yeast: identification of isoaccepting transfer RNAs

Biochemistry ◽  
1978 ◽  
Vol 17 (9) ◽  
pp. 1628-1634 ◽  
Author(s):  
Nancy C. Martin ◽  
Murray Rabinowitz
Keyword(s):  
Yeast Identification ◽  
Transfer Rnas ◽  
Mitochondrial Transfer

scholarly journals Emerging therapies for mitochondrial diseases

2018 ◽  
Vol 62 (3) ◽  
pp. 467-481 ◽  
Author(s):  
Michio Hirano ◽  
Valentina Emmanuele ◽  
Catarina M. Quinzii
Keyword(s):  
Mitochondrial Dynamics ◽  
Mitochondrial Diseases ◽  
Mitochondrial Dna Mutation ◽  
Toxic Compounds ◽  
Transfer Rnas ◽  
Dna Mutation ◽  
Emerging Therapies ◽  
Mitochondrial Transfer ◽  
Mitochondrial Replacement Therapy ◽  
Specific Disorders

For the vast majority of patients with mitochondrial diseases, only supportive and symptomatic therapies are available. However, in the last decade, due to extraordinary advances in defining the causes and pathomechanisms of these diverse disorders, new therapies are being developed in the laboratory and are entering human clinical trials. In this review, we highlight the current use of dietary supplement and exercise therapies as well as emerging therapies that may be broadly applicable across multiple mitochondrial diseases or tailored for specific disorders. Examples of non-tailored therapeutic targets include: activation of mitochondrial biogenesis, regulation of mitophagy and mitochondrial dynamics, bypass of biochemical defects, mitochondrial replacement therapy, and hypoxia. In contrast, tailored therapies are: scavenging of toxic compounds, deoxynucleoside and deoxynucleotide treatments, cell replacement therapies, gene therapy, shifting mitochondrial DNA mutation heteroplasmy, and stabilization of mutant mitochondrial transfer RNAs.

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