The Role of Herpes Simplex Virus Thymidine Kinase Expression in Pathogenesis and Latency

Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes - Frontiers of Virology ◽

10.1007/978-3-642-85004-2_5 ◽

1994 ◽

pp. 68-86 ◽

Author(s):

Richard B. Tenser

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

Role of Herpes simplex Virus Thymidine Kinase Expression in Viral Pathogenesis and Latency

Intervirology ◽

10.1159/000150188 ◽

1991 ◽

Vol 32 (2) ◽

pp. 76-92 ◽

Author(s):

Richard B. Tenser

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Viral Pathogenesis ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

Herpes simplex virus type 1 UL46 and UL47 deletion mutants lack VP11 and VP12 or VP13 and VP14, respectively, and exhibit altered viral thymidine kinase expression.

Journal of Virology ◽

10.1128/jvi.67.3.1482-1492.1993 ◽

1993 ◽

Vol 67 (3) ◽

pp. 1482-1492 ◽

Author(s):

Y Zhang ◽

J L McKnight

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Deletion Mutants ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials

Nature Medicine ◽

10.1038/15207 ◽

1999 ◽

Vol 5 (11) ◽

pp. 1256-1263 ◽

Author(s):

R. A. Dewey ◽

G. Morrissey ◽

C. M. Cowsill ◽

D. Stone ◽

F. Bolognani ◽

...

Keyword(s):

Gene Therapy ◽

Clinical Trials ◽

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Brain Inflammation ◽

Herpes Simplex Virus 1 ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

The role of herpes simplex virus thymidine kinase in the treatment of solid tumours

Expert Opinion on Investigational Drugs ◽

10.1517/13543784.8.6.777 ◽

1999 ◽

Vol 8 (6) ◽

pp. 777-785 ◽

Author(s):

Matthew JA Perry ◽

Stephen M Todryk ◽

Angus G Dalgleish

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Solid Tumours ◽

Download Full-text

Neurovirulence of herpes simplex virus type 1 depends on age in mice and thymidine kinase expression

Archives of Virology ◽

10.1007/bf01311326 ◽

1983 ◽

Vol 78 (3-4) ◽

pp. 303-308 ◽

Author(s):

T. Ben-Hur ◽

Julia Hadar ◽

Y. Shtram ◽

D. H. Gilden ◽

Y. Becker

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

Role of the viral and cellular encoded thymidine kinase in the repair of UV-irradiated herpes simplex virus

Mutation Research Letters ◽

10.1016/0165-7992(89)90108-5 ◽

1989 ◽

Vol 227 (4) ◽

pp. 263-267 ◽

Author(s):

Andrew J. Rainbow

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Download Full-text

Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.77.4.2270 ◽

1980 ◽

Vol 77 (4) ◽

pp. 2270-2273 ◽

Author(s):

L. E. Schnipper ◽

C. S. Crumpacker

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Dna Polymerase ◽

Download Full-text

Density functional studies on herpes simplex virus type 1 thymidine kinase–substrate interactions: The role of Tyr-172 and Met-128 in thymine fixation

Proteins Structure Function and Bioinformatics ◽

10.1002/(sici)1097-0134(19980601)31:4<453::aid-prot11>3.0.co;2-e ◽

1998 ◽

Vol 31 (4) ◽

pp. 453-459 ◽

Author(s):

F. Alber ◽

O. Kuonen ◽

L. Scapozza ◽

G. Folkers ◽

P. Carloni

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Density Functional ◽

Kinase Substrate ◽

Functional Studies ◽

Download Full-text

Effect of in vitro Mutations in a Vaccinia Virus Early Promoter Region Monitored by Herpes Simplex Virus Thymidine Kinase Expression in Recombinant Vaccinia Virus

Journal of General Virology ◽

10.1099/0022-1317-68-9-2299 ◽

1987 ◽

Vol 68 (9) ◽

pp. 2299-2309 ◽

Author(s):

B. E. H. Coupar ◽

D. B. Boyle ◽

G. W. Both

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Vaccinia Virus ◽

Thymidine Kinase ◽

Promoter Region ◽

Recombinant Vaccinia Virus ◽

Recombinant Vaccinia ◽

Simplex Virus ◽

Kinase Expression

Download Full-text

Quantification and Analysis of Thymidine Kinase Expression from Acyclovir-Resistant G-String Insertion and Deletion Mutants in Herpes Simplex Virus-Infected Cells

Journal of Virology ◽

10.1128/jvi.06995-11 ◽

2012 ◽

Vol 86 (8) ◽

pp. 4518-4526 ◽

Author(s):

Dongli Pan ◽

Donald M. Coen

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Deletion Mutants ◽

Insertion And Deletion ◽

Infected Cells ◽

Simplex Virus ◽

Kinase Expression

Download Full-text