Structure-activity relationship of Ca2+ channel blockers: A study using conformational analysis and chemometric methods

Activity Relationship ◽

Channel Blockers ◽

Chemometric Methods ◽

Structure Activity ◽

A study of the structure–activity relationship of GABAA–benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2008.08.072 ◽

2008 ◽

Vol 16 (19) ◽

pp. 8853-8862 ◽

Cited By ~ 6

Author(s):

Dongmei Han ◽

F. Holger Försterling ◽

Xiaoyan Li ◽

Jeffrey R. Deschamps ◽

Damon Parrish ◽

...

Keyword(s):

Low Temperature ◽

Conformational Analysis ◽

Benzodiazepine Receptor ◽

Activity Relationship ◽

Bivalent Ligands ◽

X Ray ◽

Structure Activity ◽

Synthesis and Quantitative Structure−Activity Relationship of a Novel Series of Small Conductance Ca2+-Activated K+Channel Blockers Related to Dequalinium

Journal of Medicinal Chemistry ◽

10.1021/jm950520i ◽

1996 ◽

Vol 39 (2) ◽

pp. 359-370 ◽

Cited By ~ 19

Author(s):

Dimitrios Galanakis ◽

Carole A. Davis ◽

C. Robin Ganellin ◽

Philip M. Dunn

Keyword(s):

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

K Channel ◽

Channel Blockers ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of ◽

Small Conductance

Isovanillyl sweeteners. Synthesis, conformational analysis, and structure–activity relationship of some sweet oxygen heterocycles

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29910001399 ◽

1991 ◽

pp. 1399-1406 ◽

Cited By ~ 15

Author(s):

Anna Arnoldi ◽

Angela Bassoli ◽

Lucio Merlini ◽

Enzio Ragg

Keyword(s):

Conformational Analysis ◽

Activity Relationship ◽

Structure Activity ◽

Oxygen Heterocycles ◽

Synthesis and structure-activity relationship of substituted 1,2,3,4-tetrahydroisoquinolines as N-type calcium channel blockers

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(98)00440-5 ◽

1998 ◽

Vol 8 (18) ◽

pp. 2415-2418 ◽

Cited By ~ 9

Author(s):

Po-wai Yuen ◽

Robert M. Schelkun ◽

Balazs Szoke ◽

Katalin Tarczy-Hornoch

Keyword(s):

Calcium Channel ◽

Calcium Channel Blockers ◽

Activity Relationship ◽

Channel Blockers ◽

Structure Activity ◽

ChemInform Abstract: Synthesis and Structure-Activity Relationship of Substituted 1,2,3,4-Tetrahydroisoquinolines as N-Type Calcium Channel Blockers.

ChemInform ◽

10.1002/chin.199902147 ◽

2010 ◽

Vol 30 (2) ◽

pp. no-no

Author(s):

P. YUEN ◽

R. M. SCHELKUN ◽

B. SZOKE ◽

K. TARCZY-HORNOCH

Keyword(s):

Calcium Channel ◽

Calcium Channel Blockers ◽

Activity Relationship ◽

Channel Blockers ◽

Structure Activity ◽

Synthesis and Quantitative Structure-Activity Relationship of Dequalinium Analogs as K+ Channel Blockers: Investigations on the Role of the Substituent at Position 4 of the Quinoline Ring

Journal of Medicinal Chemistry ◽

10.1021/jm00018a013 ◽

1995 ◽

Vol 38 (18) ◽

pp. 3536-3546 ◽

Cited By ~ 16

Author(s):

Dimitrios Galanakis ◽

Julie A. D. Calder ◽

C. Robin Ganellin ◽

Clive S. Owen ◽

Philip M. Dunn

Keyword(s):

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

K Channel ◽

Channel Blockers ◽

Quinoline Ring ◽

Quantitative Structure ◽

Structure Activity ◽

ChemInform Abstract: Isovanillyl Sweeteners. Synthesis, Conformational Analysis, and Structure-Activity Relationship of Some Sweet Oxygen Heterocycles.

ChemInform ◽

10.1002/chin.199149298 ◽

2010 ◽

Vol 22 (49) ◽

pp. no-no

Author(s):

A. ARNOLDI ◽

A. BASSOLI ◽

L. MERLINI ◽

E. RAGG

Keyword(s):

Conformational Analysis ◽

Activity Relationship ◽

Structure Activity ◽

Oxygen Heterocycles ◽

Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(99)00359-5 ◽

1999 ◽

Vol 9 (15) ◽

pp. 2151-2156 ◽

Cited By ~ 15

Author(s):

Lain-Yen Hu ◽

R. Todd Ryder ◽

Michael F. Rafferty ◽

David J. Dooley ◽

Joann J. Geer ◽

...

Keyword(s):

Calcium Channel ◽

Calcium Channel Blockers ◽

Activity Relationship ◽

Channel Blockers ◽

Structure Activity ◽

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽

10.1055/s-0028-1084781 ◽

2008 ◽

Vol 74 (09) ◽

Author(s):

MA Brenzan ◽

CV Nakamura ◽

BPD Filho ◽

T Ueda-Nakamura ◽

MCM Young ◽

...

Keyword(s):

Leishmania Amazonensis ◽

Activity Relationship ◽

Structure Activity ◽

Structure Activity Relationship of Kahalalide F and its Analogs Against Fusarium Spp

Planta Medica ◽

10.1055/s-2008-1075262 ◽

2008 ◽

Vol 74 (03) ◽

Author(s):

N Kasanah ◽

AG Shilabin ◽

DE Wedge ◽

MT Hamann

Keyword(s):

Activity Relationship ◽

Fusarium Spp ◽

Structure Activity ◽

Kahalalide F ◽