Ultrastructure of the arthus phenomenon in muscle

1984 ◽  
Vol 64 (2) ◽  
pp. 161-166 ◽  
Author(s):  
A. Fidziańska ◽  
H. H. Goebel ◽  
G. Osse
Keyword(s):  

1959 ◽  
Vol XXXI (II) ◽  
pp. 299-304 ◽  
Author(s):  
Jørgen Christensen
Keyword(s):  


1966 ◽  
Vol 124 (4) ◽  
pp. 733-752 ◽  
Author(s):  
Charles G. Cochrane ◽  
Barbara S. Aikin

Vascular basement membrane was disrupted in the presence of polymorphonuclear leukocytes (PMN's) during two immunologic reactions: The Arthus phenomenon and the reaction to locally injected antibody to vascular basement membrane. This disruption was evidenced by (a) the inability of the basement membrane to retain circulating carbon, by (b) loss of antigenic constituents, and by (c) electron microscopic observation showing actual gaps in the structure of the vascular basement membrane. The factors within PMN's responsible for damage to isolated glomerular basement membrane in vitro were found by isolation procedures to be cathepsins D and E. Cationic proteins of PMN's were separable from the cathepsins. While inducing vascular permeability upon injection, these basic proteins failed to inflict the severe damage to the basement membrane observed in Arthus and antibasement membrane reactions. It is concluded that the full expression of these immunologic lesions requires destruction of the basement membrane possibly brought about by cathepsins D and E. Some of the physicochemical properties of these pathologically active leukocytic factors are given.



JAMA ◽  
1931 ◽  
Vol 96 (17) ◽  
pp. 1373 ◽  
Author(s):  
I. HARRISON TUMPEER
Keyword(s):  




1933 ◽  
Vol 45 (2) ◽  
pp. 343 ◽  
Author(s):  
I. HARRISON TUMPEER
Keyword(s):  


1937 ◽  
Vol 33 (12) ◽  
pp. 1476-1481
Author(s):  
A. N. Gordienko ◽  
Z. V, Starosvetskaya

The theory of allergy has recently made great strides. Thanks to advances in the experimental study of allergy, it has become possible to explain the pathogenesis of many diseases. One of the unresolved issues of allergy is the desensitization of allergic conditions. Desensitization by Bezrekka gives good results only against general anaphylaxis and related serum sickness.



2000 ◽  
Vol 41 (2) ◽  
pp. 97-102
Author(s):  
Masayasu Mitsuya ◽  
Kayoko Wada ◽  
Hiroko Ishibashi ◽  
Shigeru Tansho ◽  
Shigeru Abe ◽  
...  
Keyword(s):  




1994 ◽  
Vol 12 (1) ◽  
pp. 31-33 ◽  
Author(s):  
L. SCHINDL ◽  
R.V. BAEHR ◽  
A. KRAUSE ◽  
H. KERN ◽  
M. SCHINDL ◽  
...  


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