Immunohistochemical examination of lung cancers using monoclonal antibodies reacting with sialosylated Lewisx and sialosylated Lewisa

1987 ◽  
Vol 410 (3) ◽  
pp. 253-261 ◽  
Author(s):  
Kiyoshi Kasai ◽  
Toru Kameya ◽  
Takashi Okuda ◽  
Paul I. Terasaki ◽  
Yuichi Iwaki
Keyword(s):  
Monoclonal Antibodies ◽  
Immunohistochemical Examination ◽  
Lung Cancers

Monoclonal antibodies against CA125-bearing antigenic molecule fragments; reactivity with mucinous ovarian tumours and lung cancers

1991 ◽  
Vol 5 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Shunsuke Imai ◽  
Hiroko Maeda ◽  
Yasuhiko Kiyozuka ◽  
Junji Morimoto ◽  
Satomi Haga ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Lung Cancers ◽  
Ovarian Tumours

Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III

1983 ◽  
Vol 220 (1) ◽  
pp. 318-320 ◽  
Author(s):  
Laura C. Huang ◽  
Manfred Brockhaus ◽  
John L. Magnani ◽  
Frank Cuttitta ◽  
Steven Rosen ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Lung Cancers

Use of a Pool of Monoclonal Antibodies in Diagnosing Cells from Serous Cavities

1993 ◽  
Vol 79 (3) ◽  
pp. 211-213
Author(s):  
Antonio Cappellari ◽  
Mariangela Bagarella ◽  
Sylvie Ménard ◽  
Marcella Calabrese ◽  
Maria Ines Colnaghi
Keyword(s):  
Monoclonal Antibodies ◽  
Traditional Method ◽  
Immunoperoxidase Technique ◽  
Malignant Cells ◽  
Lung Cancers ◽  
Epithelial Origin ◽  
Neoplastic Lesions ◽  
Immunocytochemical Method ◽  
Indirect Immunoperoxidase ◽  
Diagnostic Investigations

Aims and Background The usefulness of monoclonal antibodies that recognize markers of neoplastic lesions in complementing conventional cytology was evaluated by the avidin-biotin-peroxidase complex, indirect immunoperoxidase technique. Methods In order to enhance the sensitivity of the traditional method, a pool of seven combined monoclonal antibodies (Pool C7), which reacts specifically with cells of epithelial origin and is able to distinguish between mesothelial and malignant cells, was tested on cytologic smears of 262 serous effusions. The effusions were benign or neoplastic, mainly from breast, ovary and lung cancers. Results Immunocytochemical method showed an 100 % specificity and 100 % of predictivity whereas the sensitivity was 98 %, 96 % and 95 % for breast ovarian and lung carcinomas, respectively. Conclusions The results demonstrated that the pool when used together with conventional methods, is useful in analysis of serous effusions in diagnostic investigations.

scholarly journals THE IMMUNOHISTOCHEMICAL ASSESSMENT OF THE CHARACTER OF LYMPHOID INFILTRATION IN VARIOUS FORMS OF THYROID PATHOLOGY

2017 ◽  
pp. 27-31
Author(s):  
K. M. Butolina ◽  
S. A. Lyalikov ◽  
V. A. Basinsky ◽  
T. T. Shtabinskaya ◽  
V. S. Aleksinsky ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Thyroid Cancer ◽  
Thyroid Gland ◽  
Quantitative Assessment ◽  
Lymphocyte Subpopulations ◽  
Immunohistochemical Examination ◽  
Thyroid Pathology ◽  
Immunohistochemical Assessment ◽  
Lymphoid Infiltration ◽  
Lymphoid Infiltrates

Objective: to characterize the phenotype of lymphocytes in lymphoid infiltrates in various forms of thyroid pathology. Material and methods . The operating material of 112 cases of thyroid diseases has been studied. The immunohistochemical examination using monoclonal antibodies to the antigens CD3, CD4, CD1α, CD23, CD25, CD8 and TGF-β has been conducted. Results. The quantitative assessment of lymphocyte subpopulations in lymphoid infiltrates in the tissue of the thyroid gland in thyrotoxic goiter, autoimmune thyroiditis, nodular euthyroid goiter, and thyroid cancer has been given.

scholarly journals Immunohistochemical Examination of Novel Rat Monoclonal Antibodies against Mouse and Human Podoplanin

2012 ◽  
Vol 45 (4) ◽  
pp. 227-237 ◽  
Author(s):  
Chiaki Kaji ◽  
Yuta Tsujimoto ◽  
Mika Kato Kaneko ◽  
Yukinari Kato ◽  
Yoshihiko Sawa
Keyword(s):  
Monoclonal Antibodies ◽  
Immunohistochemical Examination
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