Decrease in plasma noradrenaline levels following long-term treatment with prindolol in patients with essential hypertension

1976 ◽  
Vol 54 (22) ◽  
pp. 1095-1105 ◽  
Author(s):  
H. M. Brecht ◽  
F. Banthien ◽  
W. Schoeppe
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Plasma Noradrenaline ◽  
Long Term Treatment ◽  
Noradrenaline Levels

Effects on haemodynamics and plasma noradrenaline levels in man of long term treatment with imipramine, haloperidol and chlorpromazine

1971 ◽  
Vol 3 (3) ◽  
pp. 163-171 ◽  
Author(s):  
C. Carlsson ◽  
S. J. Dencker ◽  
G. Grimby ◽  
J. H�ggendal ◽  
G. Johnsson
Keyword(s):  
Term Treatment ◽  
Plasma Noradrenaline ◽  
Long Term Treatment ◽  
Noradrenaline Levels

Increased Plasma Noradrenaline Concentrations in Essential Hypertension and Their Decrease after Long-Term Treatment with a β-Receptor-Blocking Agent (Prindolol)

1976 ◽  
Vol 51 (s3) ◽  
pp. 485s-488s ◽  
Author(s):  
H. M. Brecht ◽  
F. Banthien ◽  
W. Ernst ◽  
W. Schoeppe
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Nervous Activity ◽  
Blocking Agent ◽  
Term Treatment ◽  
Plasma Noradrenaline ◽  
Sympathetic Nervous Activity ◽  
Control Subjects ◽  
Long Term Treatment

1. Plasma noradrenaline was measured in fiftynine patients with mild to severe essential hypertension and in fifteen normotensive control subjects under basal and orthostatic conditions. 2. In patients with essential hypertension mean plasma noradrenaline concentrations were significantly higher than in control subjects under basal and orthostatic conditions. 3. In patients with essential hypertension basal diastolic blood pressure correlated closely with the corresponding plasma noradrenaline concentrations. 4. Long-term treatment with prindolol of patients with essential hypertension led to a significant fall in diastolic and systolic blood pressure and heart rate and to a significant decrease in plasma noradrenaline concentrations under basal and orthostatic conditions. 5. The adrenergic response to upright posture, reflected by an increase in plasma noradrenaline, was not abolished by prindolol. 6. It is concluded that the anti-hypertensive effect of prindolol in patients with essential hypertension is at least partially mediated by a decrease of sympathetic nervous activity.

Plasma Adrenaline and Noradrenaline in Essential Hypertension and after Long-Term Treatment with β-Adrenoreceptor-Blocking Agents

1978 ◽  
Vol 55 (s4) ◽  
pp. 97s-100s ◽  
Author(s):  
R. Franco-Morselli ◽  
M. Baudouin-Legros ◽  
P. Meyer
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Plasma Noradrenaline ◽  
Adrenergic System ◽  
Plasma Adrenaline ◽  
Hypertensive Patients ◽  
Control Subjects ◽  
Blocking Agents ◽  
Long Term Treatment

1. Plasma adrenaline and noradrenaline were measured in supine and upright positions in 27 essential hypertensive patients and in 12 age-matched control subjects. 2. Plasma adrenaline was markedly increased in a large proportion of patients, compared with control subjects, either in supine or in upright positions, whereas no significant differences were found in plasma noradrenaline. 3. Six hypertensive patients were chronically treated with β-adrenoreceptor-blocking agents (five with propranolol and one with pindolol). Plasma noradrenaline was not significantly changed in the supine position but was markedly increased on standing in four out of six patients. Plasma adrenaline was decreased in five out of six patients either in supine or upright positions. 4. These findings support the view that the adrenergic system participates in the mechanism of essential hypertension.

Efficacy and Tolerability of Muzolimine in the Long-Term Treatment of Essential Hypertension

1987 ◽  
pp. 317-319 ◽  
Author(s):  
M. Carnovali ◽  
C. Borgnino ◽  
E. Crespi ◽  
M. Panozzo ◽  
A. Missaglia ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

Complications in long term treatment of essential hypertension

2009 ◽  
Vol 209 (S646) ◽  
pp. 123-126
Author(s):  
H. Løken ◽  
H. & Hebnes ◽  
K. Diakonissesykehus
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals Long-term treatment of essential hypertension using nadolol and hydrochlorothiazide combined.

1979 ◽  
Vol 7 (S2) ◽  
pp. 199S-203S ◽  
Author(s):  
MM El-Mehairy ◽  
A Shaker ◽  
M Ramadan ◽  
S Hamza ◽  
SS Tadros
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

Haemodynamic and clinical effects of long-term treatment of essential hypertension with captopril

1983 ◽  
Vol 4 (7) ◽  
pp. 496-501 ◽  
Author(s):  
B. RICCIARDELLI ◽  
M. VOLPE ◽  
B. TRIMARCO ◽  
N. DE LUCA ◽  
A. CUOCOLO ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Clinical Effects ◽  
Long Term Treatment
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