Role of oxygen radicals in the microcirculatory manifestations of postischemic injury

1991 ◽  
Vol 69 (21-23) ◽  
pp. 1050-1055 ◽  
Author(s):  
M. D. Menger ◽  
H. -A. Lehr ◽  
K. Messmer
Keyword(s):  
Oxygen Radicals

Alterations in p53 gene on arsenic induced skin cancers.—possible role of oxygen radicals—

1998 ◽  
Vol 16 ◽  
pp. S50 ◽  
Author(s):  
Chikako Nishigori ◽  
Kanokvalai Kulthanan ◽  
Preya Kullavanijava ◽  
Hsin-Su yu ◽  
Sadao Imamura
Keyword(s):  
Oxygen Radicals ◽  
P53 Gene ◽  
Skin Cancers

Role of oxygen radicals in immune complex-induced enteropathy in rats

1990 ◽  
pp. 931-932
Author(s):  
T Takemura ◽  
T Yoshikawa ◽  
Y Naito ◽  
S Ueda ◽  
H Oyamada ◽  
...  
Keyword(s):  
Immune Complex ◽  
Oxygen Radicals

Potential Role of Silicon-Oxygen Radicals in Acute Lung Injury

1989 ◽  
pp. 265-272 ◽  
Author(s):  
N. S. Dalal ◽  
Xianglin Shi ◽  
V. Vallyathan
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Oxygen Radicals ◽  
Potential Role ◽  
Silicon Oxygen

Role of oxygen radicals scavenging enzymes in the protoporphyrin induced photohemolysis

1979 ◽  
Vol 35 (11) ◽  
pp. 1445-1447 ◽  
Author(s):  
A. Finazzi-Agrò ◽  
G. Floris ◽  
M. B. Fadda ◽  
C. Crifò
Keyword(s):  
Oxygen Radicals ◽  
Scavenging Enzymes

Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals

1983 ◽  
Vol 245 (2) ◽  
pp. G285-G289 ◽  
Author(s):  
D. A. Parks ◽  
D. N. Granger
Keyword(s):  
Hydroxyl Radical ◽  
Dimethyl Sulfoxide ◽  
Xanthine Oxidase ◽  
Vascular Permeability ◽  
Hydroxyl Radicals ◽  
Vascular Injury ◽  
Oxygen Radicals ◽  
Intestinal Ischemia ◽  
Xanthine Oxidase Inhibitor

The results of previous studies indicate that oxygen-derived free radicals are responsible for the increased vascular permeability produced by 1 h of intestinal ischemia. The aims of this study were 1) to test the hypothesis that the enzyme xanthine oxidase is the source of oxygen radicals in the ischemic bowel and 2) to assess the role of the hydroxyl radical in the ischemia-induced vascular injury. The capillary osmotic reflection coefficient was estimated from lymphatic protein flux data in the cat ileum for the following conditions: ischemia, ischemia plus pretreatment with allopurinol (a xanthine oxidase inhibitor), and ischemia plus pretreatment with dimethyl sulfoxide (a hydroxyl radical scavenger). The increased vascular permeability produced by ischemia was largely prevented by pretreatment with either allopurinol or dimethyl sulfoxide. These findings support the hypothesis that xanthine oxidase is the source of oxygen radicals produced during ischemia. The results also indicate that hydroxyl radicals, derived from the superoxide anion, are primarily responsible for the vascular injury associated with intestinal ischemia.

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