Quantum mechanics and geometric analysis on manifolds

1982 ◽  
Vol 21 (10-11) ◽  
pp. 803-828 ◽  
Author(s):  
Robert Hermann
Author(s):  
D.F. Clapin ◽  
V.J.A. Montpetit

Alzheimer's disease is characterized by the accumulation of abnormal filamentous proteins. The most important of these are amyloid fibrils and paired helical filaments (PHF). PHF are located intraneuronally forming bundles called neurofibrillary tangles. The designation of these structures as "tangles" is appropriate at the light microscopic level. However, localized domains within individual tangles appear to demonstrate a regular spacing which may indicate a liquid crystalline phase. The purpose of this paper is to present a statistical geometric analysis of PHF packing.


Author(s):  
George Birtwistle
Keyword(s):  

Author(s):  
A. F. J. Levi
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document