Effect of magnesium ions on red cell membrane properties

1990 ◽  
Vol 118 (3) ◽  
pp. 251-257 ◽  
Author(s):  
G. H. Beaven ◽  
J. Parmar ◽  
G. B. Nash ◽  
P. M. Bennett ◽  
W. B. Gratzer
Keyword(s):  
Cell Membrane ◽  
Membrane Properties ◽  
Red Cell ◽  
Magnesium Ions ◽  
Red Cell Membrane

scholarly journals Correction: Alterations of Red Cell Membrane Properties in Nneuroacanthocytosis

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
Author(s):  
Claudia Siegl ◽  
Patricia Hamminger ◽  
Herbert Jank ◽  
Uwe Ahting ◽  
Benedikt Bader ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Properties ◽  
Red Cell ◽  
Red Cell Membrane

A study of red cell membrane properties in relation to malarial invasion

1989 ◽  
Vol 34 (1) ◽  
pp. 63-74 ◽  
Author(s):  
Kaveri Rangachari ◽  
Gilbert H. Beaven ◽  
Gerard B. Nash ◽  
Barbara Clough ◽  
Anton R. Dluzewski ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Properties ◽  
Red Cell ◽  
Red Cell Membrane

Relation of red cell membrane properties to invasion byPlasmodium falciparum

Parasitology ◽  
1985 ◽  
Vol 91 (2) ◽  
pp. 273-280 ◽  
Author(s):  
A. R. Dluzewski ◽  
k. Rangachari ◽  
R. J. M. Wilson ◽  
W. B. Gratzer
Keyword(s):  
Cell Membrane ◽  
Substantial Reduction ◽  
Cholesterol Content ◽  
Phospholipid Bilayer ◽  
Membrane Properties ◽  
Red Cell ◽  
Red Cell Membrane ◽  
Preferred Direction ◽  
Membrane Cytoskeleton ◽  
Mechanical Rigidity

The effects of changes in red cell membrane properties on invasion byPlasmodium falciparumhave been studied by varying the cholesterol content and the intracellular concentration of polyamines. Increased cholesterol content is known to cause large reductions in the internal fluidity of the phospholipid bilayer and a change in its preferred direction of bending, but does not cause changes in gross mechanical rigidity. Polyamines, on the other hand, are thought to increase the cohesion of the membrane cytoskeleton and impede translational diffusion of transmembrane particles, as well as increase trie mechanical rigidity of the membrane. Cells with membranes augmented by 50% in cholesterol show no reduction in their susceptibility to parasitic invasion, whereas an increase in cytosolic polyamine (especially spermine) concentration leads to strong inhibition of invasion. In neither case is the development of the intracellular parasite affected. We conclude that it is the macroscopic, rather than the microscopic rheoelastic properties of the membrane that influence the invasion process. Depletion of membrane cholesterol leads to a substantial reduction in parasitaemia; it is suggested that this is linked to the reduced phosphorus incorporation into spectrin in these cells. Polyamines may exert a significant effect at physiological concentrations and the possibility must be considered that the elevated polyamine levels found in red cells in sickle cell disease may account for the protection againstP. falciparum.

scholarly journals Alterations of Red Cell Membrane Properties in Nneuroacanthocytosis

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e76715 ◽  
Author(s):  
Claudia Siegl ◽  
Patricia Hamminger ◽  
Herbert Jank ◽  
Uwe Ahting ◽  
Benedikt Bader ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Properties ◽  
Red Cell ◽  
Red Cell Membrane

Basis of unique red cell membrane properties in hereditary ovalocytosis

1992 ◽  
Vol 223 (4) ◽  
pp. 949-958 ◽  
Author(s):  
Ann E. Schofield ◽  
M.J.A. Tanner ◽  
Jennifer C. Pinder ◽  
Barbara Clough ◽  
P.M. Bayley ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Membrane Properties ◽  
Red Cell ◽  
Red Cell Membrane
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