Extreme diffuse adenomatous hyperplasia of Brunner's glands: Case report

1990 ◽  
Vol 15 (1) ◽  
pp. 285-287 ◽  
Author(s):  
W. J. J. Rooij ◽  
J. J. Horst ◽  
W. N. H. M. Stuifbergen ◽  
P. M. Pijpers

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Mohammed A Bakir ◽  
Mohammed Y AlYousef ◽  
Fahad I Alsohaibani ◽  
Khaled O Alsaad

Abstract Proliferative lesions of the Brunner’s glands are uncommonly encountered lesions of the small intestine, originating from the deeply seated mucosal and submucosal Brunner’s glands, mainly in the duodenum. The vast majorities of these lesions are benign and include Brunner’s glands hyperplasia (adenomas/nodules) and hamartomas. The etiology and pathogenesis of these lesions are not fully understood, and the diagnosis can sometimes be challenging. We report a case of Brunner’s gland hamartoma in a 57-year-old man who presented with chronic dyspepsia, hematemesis and weight loss. Endoscopic and radiological investigations show a submucosal polypoid lesion at the first part of the duodenum. Routine endoscopic biopsies demonstrated normal duodenal mucosa. The lesion considered endoscopically unresectable and was surgically resected. Frozen section examination and intraoperative consultation showed unremarkable duodenal mucosa and histologically bland Brunner’s glands.



1981 ◽  
Vol 394 (1-2) ◽  
pp. 75-87 ◽  
Author(s):  
M. Stolte ◽  
H. Schwabe ◽  
H. Prestele


The Lancet ◽  
1903 ◽  
Vol 162 (4168) ◽  
pp. 176-177


Andrologia ◽  
2013 ◽  
Vol 46 (4) ◽  
pp. 449-452 ◽  
Author(s):  
H. Ogul ◽  
B. Pirimoglu ◽  
G. A. Taskın ◽  
U. Bayraktutan ◽  
M. Ozgokce ◽  
...  


2016 ◽  
Vol 83 (6) ◽  
pp. 1295-1296 ◽  
Author(s):  
Jian Tang ◽  
Hua Wang ◽  
Feng Liu ◽  
Zhaoshen Li


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Matthias Hepprich ◽  
Kwadwo Antwi ◽  
Beatrice Waser ◽  
Jean Claude Reubi ◽  
Damian Wild ◽  
...  

Severe cases of postprandial hypoglycaemia after bariatric surgery can be a diagnostic and therapeutic challenge. The diagnostic role of 68Ga-DOTA-Exendin-4 PET/CT in postbariatric hypoglycaemia for further treatment decisions is unclear. We present a case of a 50-year-old woman with frequent and severe postprandial hypoglycaemic (≤2.5 mmol/L) episodes starting three years after Roux-Y gastric bypass. Despite strict dietary adherence and several medical therapies, the patient remained severely affected, and 68Ga-DOTA-Exendin-4 PET/CT was performed to exclude atypical presentation of an insulinoma or nesidioblastosis. No pancreatic abnormalities were found, but intensive tracer accumulation in the first and second part of the duodenum was detected, which proved to be hyperplastic Brunner’s glands on histology and were strongly positive for the glucagon-like peptide-1 receptor. This case provides histopathological verification that duodenal 68Ga-DOTA-Exendin-4 uptake is caused by uptake in Brunner’s glands and points to a potential relationship between bariatric surgery and Brunner’s glands.



1934 ◽  
Vol 39 (2) ◽  
pp. 255-276 ◽  
Author(s):  
H. W. Florey ◽  
H. E. Harding


The Lancet ◽  
1968 ◽  
Vol 291 (7546) ◽  
pp. 816
Author(s):  
G. Astaldi ◽  
G. Meardi ◽  
P.L. Taverna ◽  
R. Airò


1968 ◽  
Vol 13 (11) ◽  
pp. 935-940 ◽  
Author(s):  
G. Astaldi ◽  
P. L. Taverna ◽  
G. Meardi ◽  
R. Airo


1970 ◽  
Vol 167 (4) ◽  
pp. 473-487 ◽  
Author(s):  
William J. Krause


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