Basal tone and responsiveness of isolated perfused collateral coronary arteries from the dog

1982 ◽  
Vol 394 (S1) ◽  
pp. R15-R15
Author(s):  
G. Weinheimer ◽  
K. Golenhofen ◽  
K. Mandrek
Keyword(s):  
Coronary Arteries ◽  
Basal Tone

Importance of residual stress and basal tone in healthy and pathological human coronary arteries

2021 ◽  
pp. 433-461
Author(s):  
Jean-Louis Martiel ◽  
Gérard Finet ◽  
Gerhard A. Holzapfel ◽  
Matthias Stuber ◽  
Takeo Matsumoto ◽  
...  
Keyword(s):  
Residual Stress ◽  
Coronary Arteries ◽  
Basal Tone

scholarly journals Effects of L- and D- arginine on the basal tone of diseased coronary arteries and their responses to substance P

1998 ◽  
Vol 31 ◽  
pp. 328
Author(s):  
C. Tontolouris ◽  
D. Tousoulis ◽  
T. Crake ◽  
G. Katsimaglis ◽  
A. Androulakis ◽  
...  
Keyword(s):  
Substance P ◽  
Coronary Arteries ◽  
Basal Tone

Increased basal tone and hyperresponsiveness to acetylcholine and ergonovine in spasm-related coronary arteries in patients with variant angina

1996 ◽  
Vol 55 (2) ◽  
pp. 117-126 ◽  
Author(s):  
Simon Jong-Koo Lee ◽  
Seung-Jung Park ◽  
Seong-Wook Park ◽  
Jae-Joong Kim ◽  
Jae-Kwan Song ◽  
...  
Keyword(s):  
Coronary Arteries ◽  
Variant Angina ◽  
Basal Tone

Neuronal NOS-dependent dilation to flow in coronary arteries of male eNOS-KO mice

2002 ◽  
Vol 282 (2) ◽  
pp. H429-H436 ◽  
Author(s):  
An Huang ◽  
Dong Sun ◽  
Edward G. Shesely ◽  
Ellen M. Levee ◽  
Akos Koller ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Coronary Arteries ◽  
No Synthase ◽  
Simultaneous Administration ◽  
Wild Type ◽  
Basal Tone ◽  
Neuronal Nos ◽  
Immunohistochemical Evidence ◽  
Endothelial Nitric Oxide ◽  
Arterial Endothelium

Flow-induced dilation was examined in isolated coronary arteries of endothelial nitric oxide (NO) synthase knockout mice (eNOS-KO) and wild-type (WT) mice. The basal tone of arteries (percentage of passive diameter) was significantly greater in eNOS-KO than in WT mice; their flow-induced dilations, however, were similar. Endothelial removal eliminated the dilations in vessels of both strains of mice. In arteries of WT mice, N ω-nitro-l-arginine methyl ester (l-NAME) (10−4 M) or indomethacin (10−5 M) alone, inhibited flow-induced dilation by ∼50%, whereas their simultaneous administration abolished the responses. In arteries of eNOS-KO mice, flow-induced dilation was inhibited by ∼40% with l-NAME. The residual portion (60%) of the response was eliminated by the additional administration of indomethacin. 7-Nitroindazole (10−4 M) attenuated flow-induced dilation by ∼40% in arteries of eNOS-KO mice, but did not affect responses in those of WT mice. 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (3 × 10−5 M) inhibited thel-NAME/7-nitroindazole-sensitive portion of the responses in arteries of eNOS-KO mice. Immunohistochemical evidence confirms the presence of neuronal NOS (nNOS) in the arterial endothelium of eNOS-KO mice. In conclusion, nNOS-derived NO, via activation of cGMP, together with prostaglandins, maintains flow-induced dilation in coronary arteries of male eNOS-KO mice.

scholarly journals Effects of L- and D-arginine on the basal tone of human diseased coronary arteries and their responses to substance P

Heart ◽  
1999 ◽  
Vol 81 (5) ◽  
pp. 505-511 ◽  
Author(s):  
D Tousoulis ◽  
C Tentolouris ◽  
T Crake ◽  
G Katsimaglis ◽  
C Stefanadis ◽  
...  
Keyword(s):  
Substance P ◽  
Coronary Arteries ◽  
Basal Tone
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