Once-daily oral nitrates preferred in angina pectoris

1997 ◽  
Vol 137 (1) ◽  
pp. 9-9
Keyword(s):  
Angina Pectoris ◽  
Once Daily

A comparison of once daily bisoprolol, 5 and 10 mg, and atenolol 100 mg in the treatment of angina pectoris

1987 ◽  
Vol 8 (suppl M) ◽  
pp. 37-42 ◽  
Author(s):  
M. B. Maltz ◽  
D. S. Dymond ◽  
A. W. Nathan ◽  
A. J. Camm
Keyword(s):  
Angina Pectoris ◽  
Once Daily

Compliance as a Factor in the Development of Nitrate Tolerance: A Patient Investigation

1993 ◽  
Vol 21 (1) ◽  
pp. 51-57 ◽  
Author(s):  
P Löfdahl
Keyword(s):  
Angina Pectoris ◽  
Nitrate Concentration ◽  
Nitrate Tolerance ◽  
Isosorbide Mononitrate ◽  
Dosing Regimen ◽  
Once Daily ◽  
Telephone Interviews ◽  
The Times ◽  
Plasma Nitrate ◽  
Long Acting

Telephone interviews were conducted to establish the prescribing instructions given by experienced physicians to patients with angina pectoris treated with long-acting nitrates. In addition, the times of day when doses were taken were recorded. The aim of the study was to determine whether or not an asymmetric dosing regimen was being followed by the patients. The majority (62.7%) of patients were being treated with 5-isosorbide mononitrate taken orally twice daily. All but two took the correct number of tablets, but more than 50% of these patients were not taking the second tablet at the correct time to achieve the recommended 6 − 8-h period during which the plasma nitrate concentration was sufficiently low to avoid nitrate tolerance. Possible explanations for the incorrect use of the prescribed drug may be that the patients did not understand the physician's instructions and did not appreciate the importance of rigidly adhering to these instructions. A more satisfactory approach, with improved patient compliance, may be a once-daily dosing regimen.

Age-Dependent Therapeutic Effects of Once-Daily Molsidomine Used as an Add-On Treatment in Patients with Stable Angina pectoris

Heart Drug ◽  
2004 ◽  
Vol 4 (4) ◽  
pp. 184-189 ◽  
Author(s):  
Roger Messin ◽  
Fabienne Carreer-Bruhwyler ◽  
Claude Dubois ◽  
Jean-Pierre Famaey ◽  
Joseph Géczy
Keyword(s):  
Angina Pectoris ◽  
Stable Angina ◽  
Therapeutic Effects ◽  
Stable Angina Pectoris ◽  
Once Daily ◽  
Age Dependent
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