By means of infinite-dimensional nuclear spaces, we generalize important results on the representation of the Weyl commutation relations. For this purpose, we construct a new nuclear Lie group generalizing the groups introduced by Parthasarathy [An Introduction to Quantum Stochastic Calculus (Birkhäuser, 1992)] and Gelfand–Vilenkin [Generalized Functions (Academic Press, 1964)] (see Ref. 15). Then we give an explicit construction of Weyl representations generated from a non-Fock representation. Moreover, we characterize all these Weyl representations in quantum white noise setting.