scholarly journals Base excision repair and design of small molecule inhibitors of human DNA polymerase β

2010 ◽  
Vol 67 (21) ◽  
pp. 3633-3647 ◽  
Author(s):  
Samuel H. Wilson ◽  
William A. Beard ◽  
David D. Shock ◽  
Vinod K. Batra ◽  
Nisha A. Cavanaugh ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Small Molecule ◽  
Base Excision Repair ◽  
Small Molecule Inhibitors ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Human Dna ◽  
Base Excision

scholarly journals The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

2005 ◽  
Vol 389 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Ekaterina SMIRNOVA ◽  
Magali TOUEILLE ◽  
Enni MARKKANEN ◽  
Ulrich HÜBSCHER
Keyword(s):  
Quality Control ◽  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Ligase ◽  
Dna Polymerase Β ◽  
Flap Endonuclease 1 ◽  
Important Target ◽  
Dna Ligase I ◽  
Base Excision

The human checkpoint sensor and alternative clamp Rad9–Rad1–Hus1 can interact with and specifically stimulate DNA ligase I. The very recently described interactions of Rad9–Rad1–Hus1 with MutY DNA glycosylase, DNA polymerase β and Flap endonuclease 1 now complete our view that the long-patch base excision machinery is an important target of the Rad9–Rad1–Hus1 complex, thus enhancing the quality control of DNA.

scholarly journals DNA polymerase β outperforms DNA polymerase γ in key mitochondrial base excision repair activities

DNA Repair ◽  
2021 ◽  
Vol 99 ◽  
pp. 103050
Author(s):  
Beverly A. Baptiste ◽  
Stephanie L. Baringer ◽  
Tomasz Kulikowicz ◽  
Joshua A. Sommers ◽  
Deborah L. Croteau ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Base Excision ◽  
Dna Polymerase Γ

DNA Polymerase β Promotes Recruitment of DNA Ligase IIIα−XRCC1 to Sites of Base Excision Repair

Biochemistry ◽  
2005 ◽  
Vol 44 (31) ◽  
pp. 10613-10619 ◽  
Author(s):  
Jason L. Parsons ◽  
Irina I. Dianova ◽  
Sarah L. Allinson ◽  
Grigory L. Dianov
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Ligase ◽  
Dna Polymerase Β ◽  
Base Excision

scholarly journals A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase β

2010 ◽  
Vol 39 (8) ◽  
pp. 3156-3165 ◽  
Author(s):  
De-Sheng Pei ◽  
Xiao-Jie Yang ◽  
Wei Liu ◽  
Jeroen E. J. Guikema ◽  
Carol E. Schrader ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Ap Endonuclease ◽  
Regulatory Circuit ◽  
Ap Endonuclease 1 ◽  
Base Excision

scholarly journals Protection against Methylation-induced Cytotoxicity by DNA Polymerase β-Dependent Long Patch Base Excision Repair

2000 ◽  
Vol 275 (3) ◽  
pp. 2211-2218 ◽  
Author(s):  
Julie K. Horton ◽  
Rajendra Prasad ◽  
Esther Hou ◽  
Samuel H. Wilson
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Base Excision

scholarly journals Apurinic/Apyrimidinic Endonuclease (APE/REF-1) Haploinsufficient Mice Display Tissue-specific Differences in DNA Polymerase β-Dependent Base Excision Repair

2004 ◽  
Vol 279 (18) ◽  
pp. 18425-18433 ◽  
Author(s):  
Julian J. Raffoul ◽  
Diane C. Cabelof ◽  
Jun Nakamura ◽  
Lisiane B. Meira ◽  
Errol C. Friedberg ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Tissue Specific ◽  
Base Excision

scholarly journals Role of DNA Polymerase β in the Excision Step of Long Patch Mammalian Base Excision Repair

1999 ◽  
Vol 274 (20) ◽  
pp. 13741-13743 ◽  
Author(s):  
Grigory L. Dianov ◽  
Rajendra Prasad ◽  
Samuel H. Wilson ◽  
Vilhelm A. Bohr
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Polymerase Β ◽  
Base Excision

Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair

DNA Repair ◽  
2012 ◽  
Vol 11 (4) ◽  
pp. 367-373 ◽  
Author(s):  
Lidia V. Skosareva ◽  
Natalia A. Lebedeva ◽  
Nadejda I. Rechkunova ◽  
Alexander Kolbanovskiy ◽  
Nicholas E. Geacintov ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Adduct ◽  
Lesion Bypass ◽  
Human Dna ◽  
Dna Polymerase Λ ◽  
Base Excision

scholarly journals Long Patch Base Excision Repair Compensates for DNA Polymerase β Inactivation by the C4′-Oxidized Abasic Site

Biochemistry ◽  
2011 ◽  
Vol 50 (1) ◽  
pp. 136-143 ◽  
Author(s):  
Aaron C. Jacobs ◽  
Cortney R. Kreller ◽  
Marc M. Greenberg
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Abasic Site ◽  
Dna Polymerase Β ◽  
Oxidized Abasic Site ◽  
Base Excision
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