TSC-insensitive Rheb mutations induce oncogenic transformation through a combination of constitutively active mTORC1 signalling and proteome remodelling

2021 ◽  
Author(s):  
Jianling Xie ◽  
Stuart P. De Poi ◽  
Sean J. Humphrey ◽  
Leanne K. Hein ◽  
John B. Bruning ◽  
...  
Keyword(s):  
Oncogenic Transformation ◽  
Constitutively Active

scholarly journals Constitutively active Rheb induces oncogenic transformation

Oncogene ◽  
2008 ◽  
Vol 27 (43) ◽  
pp. 5729-5740 ◽  
Author(s):  
H Jiang ◽  
P K Vogt
Keyword(s):  
Oncogenic Transformation ◽  
Constitutively Active

Constitutively active phosphatidlyinositol 3-kinase (Pl 3-K) and Akt are sufficient to stimulate NHE3: Insights in mechanisms of NHE3 stimulation

2001 ◽  
Vol 120 (5) ◽  
pp. A696-A696
Author(s):  
W KWON ◽  
D JOHNS ◽  
M CAVET ◽  
J PARK ◽  
P TSICHLIS ◽  
...  
Keyword(s):  
Constitutively Active

Antibodies directed against retained intron 4 of the constitutively active CCK-2 receptor bind to a tumour-specific epitope

2001 ◽  
Vol 120 (5) ◽  
pp. A496-A496 ◽  
Author(s):  
P CLARKE ◽  
S GRIMES ◽  
D MCWILLIAMS ◽  
W KLEIE ◽  
K KHAN ◽  
...  
Keyword(s):  
Specific Epitope ◽  
Retained Intron ◽  
Intron 4 ◽  
Constitutively Active

A p19Arf and Aurka mediated G2/M arrest prevents oncogenic transformation of p53 deficient hepatocytes

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
D Dauch ◽  
T Wuestefeld ◽  
TW Kang ◽  
R Rudalska ◽  
A Hohmeyer ◽  
...  
Keyword(s):  
Oncogenic Transformation
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