Arrhythmia Risk Stratification with Regard to Prophylactic Implantable Defibrillator Therapy in Patients with Dilated Cardiomyopathy

Herz ◽  
2004 ◽  
Vol 29 (3) ◽  
pp. 348-352 ◽  
Author(s):  
Wolfram Grimm ◽  
Peter Alter ◽  
Bernhard Maisch
Circulation ◽  
2003 ◽  
Vol 108 (23) ◽  
pp. 2883-2891 ◽  
Author(s):  
Wolfram Grimm ◽  
Michael Christ ◽  
Jennifer Bach ◽  
Hans-Helge Müller ◽  
Bernhard Maisch

Author(s):  
Marianna Leopoulou ◽  
Jo Ann LeQuang ◽  
Joseph V. Pergolizzi ◽  
Peter Magnusson

Dilated cardiomyopathy (DCM) is characterized by the phenotype of a dilated left ventricle with systolic dysfunction. It is classified as hereditary when it is deemed of genetic origin; more than 50 genes are reported to be related to the condition. Symptoms include, among others, dyspnea, fatigue, arrhythmias, and syncope. Unfortunately, sudden cardiac death may be the first manifestation of the disease. Risk stratification regarding sudden death in hereditary DCM as well as preventive management poses a challenge due to the heterogeneity of the disease. The purpose of this chapter is to present the epidemiology, risk stratification, and preventive strategies of sudden cardiac death in hereditary DCM.


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