Phase I, dose escalation and pharmacokinetic study of cediranib (RECENTIN™), a highly potent and selective VEGFR signaling inhibitor, in Japanese patients with advanced solid tumors

2009 ◽  
Vol 64 (6) ◽  
pp. 1165-1172 ◽  
Author(s):  
Noboru Yamamoto ◽  
Tomohide Tamura ◽  
Nobuyuki Yamamoto ◽  
Kazuhiko Yamada ◽  
Yasuhide Yamada ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Japanese Patients ◽  
Advanced Solid Tumors

A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors

2009 ◽  
Vol 66 (3) ◽  
pp. 441-448 ◽  
Author(s):  
E. Gabriela Chiorean ◽  
Srikar Malireddy ◽  
Anne E. Younger ◽  
David R. Jones ◽  
Mary-Jane Waddell ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Advanced Solid Tumors

scholarly journals A Phase I, dose-finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors*,†

2012 ◽  
Vol 103 (3) ◽  
pp. 504-509 ◽  
Author(s):  
Noboru Yamamoto ◽  
Hiroshi Nokihara ◽  
Yasuhide Yamada ◽  
Yasushi Goto ◽  
Maki Tanioka ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Japanese Patients ◽  
Dose Finding ◽  
Advanced Solid Tumors

scholarly journals Phase I dose‐escalation study of capmatinib ( INC 280) in Japanese patients with advanced solid tumors

2019 ◽  
Vol 110 (4) ◽  
pp. 1340-1351 ◽  
Author(s):  
Taito Esaki ◽  
Fumihiko Hirai ◽  
Akitaka Makiyama ◽  
Takashi Seto ◽  
Hideaki Bando ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Japanese Patients ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors

2011 ◽  
Vol 69 (4) ◽  
pp. 1013-1020 ◽  
Author(s):  
Sukhmani K. Padda ◽  
Yelena Krupitskaya ◽  
Laveena Chhatwani ◽  
George A. Fisher ◽  
Alexander D. Colevas ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Advanced Solid Tumors

scholarly journals Phase I dose‐escalation study of buparlisib ( BKM 120), an oral pan‐class I PI 3K inhibitor, in Japanese patients with advanced solid tumors

2014 ◽  
Vol 105 (3) ◽  
pp. 347-353 ◽  
Author(s):  
Yuichi Ando ◽  
Megumi Inada‐Inoue ◽  
Ayako Mitsuma ◽  
Takayuki Yoshino ◽  
Atsushi Ohtsu ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Japanese Patients ◽  
Class I ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study

scholarly journals Phase I dose escalation and pharmacokinetic study of oral enzastaurin (LY317615) in advanced solid tumors

2010 ◽  
Vol 101 (10) ◽  
pp. 2193-2199 ◽  
Author(s):  
Toru Mukohara ◽  
Shunji Nagai ◽  
Minori Koshiji ◽  
Kenichi Yoshizawa ◽  
Hironobu Minami
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Advanced Solid Tumors

scholarly journals Phase I Dose-Escalation and Pharmacokinetic Study of Dasatinib in Patients with Advanced Solid Tumors

2009 ◽  
Vol 15 (19) ◽  
pp. 6232-6240 ◽  
Author(s):  
George D. Demetri ◽  
Patricia Lo Russo ◽  
Iain R.J. MacPherson ◽  
Ding Wang ◽  
Jeffrey A. Morgan ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Dose Escalation ◽  
Advanced Solid Tumors

scholarly journals Phase I dose escalation (esc) trial of weekly intravenous (i.v.) BI 836845 in Japanese patients (pts) with advanced solid tumors

2016 ◽  
Vol 27 ◽  
pp. vi119 ◽  
Author(s):  
T. Doi ◽  
K. Shitara ◽  
Y. Naito ◽  
Y. Kuboki ◽  
T. Kojima ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Japanese Patients ◽  
Advanced Solid Tumors
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