Evolution of ragweed pollen concentrations, sensitization and related allergic clinical symptoms in Parma (northern Italy)

Aerobiologia ◽  
2011 ◽  
Vol 28 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Roberto Albertini ◽  
Manuela Ugolotti ◽  
Silvia Peveri ◽  
Maria Teresa Valenti ◽  
Isabella Usberti ◽  
...  
2012 ◽  
Vol 56 (6) ◽  
pp. 1145-1158 ◽  
Author(s):  
Maja Telišman Prtenjak ◽  
Lidija Srnec ◽  
Renata Peternel ◽  
Valentina Madžarević ◽  
Ivana Hrga ◽  
...  

2016 ◽  
Vol 13 (9) ◽  
pp. 2769-2786 ◽  
Author(s):  
Li Liu ◽  
Fabien Solmon ◽  
Robert Vautard ◽  
Lynda Hamaoui-Laguel ◽  
Csaba Zsolt Torma ◽  
...  

Abstract. Common ragweed (Ambrosia artemisiifolia L.) is a highly allergenic and invasive plant in Europe. Its pollen can be transported over large distances and has been recognized as a significant cause of hay fever and asthma (D'Amato et al., 2007; Burbach et al., 2009). To simulate production and dispersion of common ragweed pollen, we implement a pollen emission and transport module in the Regional Climate Model (RegCM) version 4 using the framework of the Community Land Model (CLM) version 4.5. In this online approach pollen emissions are calculated based on the modelling of plant distribution, pollen production, species-specific phenology, flowering probability, and flux response to meteorological conditions. A pollen tracer model is used to describe pollen advective transport, turbulent mixing, dry and wet deposition. The model is then applied and evaluated on a European domain for the period 2000–2010. To reduce the large uncertainties notably due to the lack of information on ragweed density distribution, a calibration based on airborne pollen observations is used. Accordingly a cross validation is conducted and shows reasonable error and sensitivity of the calibration. Resulting simulations show that the model captures the gross features of the pollen concentrations found in Europe, and reproduce reasonably both the spatial and temporal patterns of flowering season and associated pollen concentrations measured over Europe. The model can explain 68.6, 39.2, and 34.3 % of the observed variance in starting, central, and ending dates of the pollen season with associated root mean square error (RMSE) equal to 4.7, 3.9, and 7.0 days, respectively. The correlation between simulated and observed daily concentrations time series reaches 0.69. Statistical scores show that the model performs better over the central Europe source region where pollen loads are larger and the model is better constrained. From these simulations health risks associated to common ragweed pollen spread are evaluated through calculation of exposure time above health-relevant threshold levels. The total risk area with concentration above 5 grains m−3 takes up 29.5 % of domain. The longest exposure time occurs on Pannonian Plain, where the number of days per year with the daily concentration above 20 grains m−3 exceeds 30.


2014 ◽  
Vol 476-477 ◽  
pp. 542-552 ◽  
Author(s):  
Zoltán Csépe ◽  
László Makra ◽  
Dimitris Voukantsis ◽  
István Matyasovszky ◽  
Gábor Tusnády ◽  
...  

2017 ◽  
Vol 133 (1-2) ◽  
pp. 277-295 ◽  
Author(s):  
István Matyasovszky ◽  
László Makra ◽  
Gábor Tusnády ◽  
Zoltán Csépe ◽  
László G. Nyúl ◽  
...  

1989 ◽  
Vol 3 (4) ◽  
pp. 211-215 ◽  
Author(s):  
Pierre Michel Bédard ◽  
Marie Jobin ◽  
Lorraine Clement ◽  
Walid Mourad ◽  
Jacques Hébert

An increased nonspecific nasal reactivity (NSNR) to histamine or to methacholine has been reported in patients with rhinitis, but its contribution to clinical symptoms remains unclear. In the present study, the NSNR to histamine, defined as the concentration of histamine necessary to induce, after a topical challenge, a 75% decrease in nasal airflow (PC75), was significantly more severe in a group of ragweed-allergic subjects during natural exposure to pollen (PC75 = 4.65 mg/ml) than in normal volunteers (PC75 = 12.9 mg/ml, p < 0.0001). However, the basal nasal airflow rates of the two groups were not significantly different (290 and 339 cc). The NSNR correlated with skin sensitivity to ragweed (r = 0.46, p < 0.0021) or with the IgE antibody (Ab) levels (r = 0.42, p < 0.01) but not with the symptom scores. Finally, after the pollen season, the allergic group's nasal sensitivity to histamine improved significantly (PC75 = 4.65 to 9.35 mg/ml, p = 0.03) but remained different from that of the control group (13.19 mg/ml, p = 0.04).


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