Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation

Mitochondrial calcium uniporter inhibition attenuates mouse bone marrow-derived mast cell degranulation induced by beta-1,3-glucan

Korean Journal of Physiology and Pharmacology ◽

10.4196/kjpp.2016.20.2.213 ◽

2016 ◽

Vol 20 (2) ◽

pp. 213 ◽

Cited By ~ 4

Author(s):

Dang Van Cuong ◽

Hyoung Kyu Kim ◽

Jubert Marquez ◽

Nari Kim ◽

Kyung Soo Ko ◽

...

Keyword(s):

Bone Marrow ◽

Mast Cell ◽

Mast Cell Degranulation ◽

Mitochondrial Calcium ◽

Mouse Bone Marrow ◽

Aloe-emodin, a naturally occurring anthraquinone, is a highly potent mast cell stabilizer through activating mitochondrial calcium uniporter

Biochemical Pharmacology ◽

10.1016/j.bcp.2021.114476 ◽

2021 ◽

Vol 186 ◽

pp. 114476

Author(s):

Yuan Gao ◽

Xiaoyu Zhang ◽

Ximeng Li ◽

Ruijuan Qi ◽

Yixin Han ◽

...

Keyword(s):

Mast Cell ◽

Mitochondrial Calcium ◽

Mast Cell Stabilizer ◽

Calcium Uniporter ◽

Naturally Occurring ◽

Aloe Emodin

288-LB: Effects of the Hepatic Mitochondrial Calcium Uniporter on Hepatic Gluconeogenesis and Mitochondrial Metabolism in Awake Mice

Diabetes ◽

10.2337/db19-288-lb ◽

2019 ◽

Vol 68 (Supplement 1) ◽

pp. 288-LB

Author(s):

JI EUN LEE ◽

LEIGH GOEDEKE ◽

YE ZHANG ◽

RACHEL J. PERRY ◽

RUSSELL GOODMAN ◽

...

Keyword(s):

Mitochondrial Metabolism ◽

Mitochondrial Calcium ◽

Hepatic Gluconeogenesis ◽

Faculty Opinions recommendation of A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11446956.14779099 ◽

2011 ◽

Author(s):

Gerald Zamponi

Keyword(s):

Mitochondrial Calcium ◽

Inner Membrane ◽

Faculty Opinions recommendation of Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11546956.14463054 ◽

2011 ◽

Author(s):

Hugo Bellen ◽

Manish Jaiswal

Keyword(s):

Mitochondrial Calcium ◽

Integrative Genomics ◽

Essential Component ◽

Faculty Opinions recommendation of Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11546956.12612054 ◽

2011 ◽

Author(s):

Eduardo Rial

Keyword(s):

Mitochondrial Calcium ◽

Integrative Genomics ◽

Essential Component ◽

Faculty Opinions recommendation of Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.11546956.12595054 ◽

2011 ◽

Author(s):

Markus Hoth ◽

Ivan Bogeski

Keyword(s):

Mitochondrial Calcium ◽

Integrative Genomics ◽

Essential Component ◽

Cobalt amine complexes and Ru265 interact with the DIME region of the mitochondrial calcium uniporter

Chemical Communications ◽

10.1039/d1cc01623g ◽

2021 ◽

Author(s):

Joshua J. Woods ◽

Madison X. Rodriguez ◽

Chen-Wei Tsai ◽

Ming-Feng Tsai ◽

Justin J. Wilson

Keyword(s):

Mechanisms Of Action ◽

Mitochondrial Calcium ◽

Amine Complexes ◽

The MCU-inhibitory properties and mechanisms of action of Co3+ amine complexes and Ru265 are described.

Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter

Cell Reports ◽

10.1016/j.celrep.2021.109275 ◽

2021 ◽

Vol 35 (12) ◽

pp. 109275

Author(s):

Agnese De Mario ◽

Anna Tosatto ◽

Julia Marie Hill ◽

Janos Kriston-Vizi ◽

Robin Ketteler ◽

...

Keyword(s):

Mitochondrial Calcium ◽

Functional Validation ◽

The effect of DS16570511, a new inhibitor of mitochondrial calcium uniporter, on calcium homeostasis, metabolism, and functional state of cultured cortical neurons and isolated brain mitochondria

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/j.bbagen.2021.129847 ◽

2021 ◽

Vol 1865 (5) ◽

pp. 129847

Author(s):

Konstantin N. Belosludtsev ◽

Rinat R. Sharipov ◽

Dmitry P. Boyarkin ◽

Natalia V. Belosludtseva ◽

Mikhail V. Dubinin ◽

...

Keyword(s):

Functional State ◽

Calcium Homeostasis ◽

Cortical Neurons ◽

Brain Mitochondria ◽

Mitochondrial Calcium ◽

Calcium Uniporter ◽

Cultured Cortical Neurons