The Quantitative Prediction of CYP-mediated Drug Interaction by Physiologically Based Pharmacokinetic Modeling

Quantitative Prediction ◽

Physiologically Based

Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb-Drug Interaction

10.1038/psp.2013.69 ◽

2014 ◽

Vol 3 (3) ◽

pp. 107 ◽

Cited By ~ 25

Author(s):

SJ Brantley ◽

BT Gufford ◽

R Dua ◽

DJ Fediuk ◽

TN Graf ◽

...

Keyword(s):

Drug Interaction ◽

Quantitative Prediction ◽

Modeling Framework ◽

Physiologically Based

Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug–Drug Interaction Potentials

Pharmaceutical Research ◽

10.1007/s11095-018-2511-5 ◽

2018 ◽

Vol 35 (12) ◽

Author(s):

Su-jin Rhee ◽

Hyun A. Lee ◽

Soyoung Lee ◽

Eunwoo Kim ◽

Inseung Jeon ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potentials ◽

Physiologically Based ◽

Physiologically based pharmacokinetic modeling for assessing the clinical drug–drug interaction of alisporivir

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2014.06.021 ◽

2014 ◽

Vol 63 ◽

pp. 103-112 ◽

Cited By ~ 8

Author(s):

Binfeng Xia ◽

Avantika Barve ◽

Tycho Heimbach ◽

Tao Zhang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interaction ◽

Physiologically Based ◽

Drug Drug Interaction ◽

Clinical Drug

Physiologically based pharmacokinetic modeling of the drug drug interaction between rifampin and SGLT2 inhibitors: The contribution of CYP induction to the observed interaction

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2017.11.168 ◽

2018 ◽

Vol 33 (1) ◽

pp. S48-S49

Author(s):

Ernesto Callegari ◽

Jian Lin ◽

Susanna Tse ◽

Theunis C. Goosen ◽

Vaishali Sahasrabudhe ◽

...

Keyword(s):

Drug Interaction ◽

Sglt2 Inhibitors ◽

Cyp Induction ◽

Physiologically Based ◽

Evaluation of the Drug–Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP ‐5862, Using a Physiologically‐Based Pharmacokinetic Modeling Approach

10.1002/psp4.12408 ◽

2019 ◽

Vol 8 (7) ◽

pp. 489-499 ◽

Cited By ~ 1

Author(s):

Diansong Zhou ◽

Terry Podoll ◽

Yan Xu ◽

Ganesh Moorthy ◽

Karthick Vishwanathan ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Active Metabolite ◽

Modeling Approach ◽

Physiologically Based ◽

Physiologically‐Based Pharmacokinetic Modeling of the Drug–Drug Interaction of the UGT Substrate Ertugliflozin Following Co‐Administration with the UGT Inhibitor Mefenamic Acid

10.1002/psp4.12581 ◽

2020 ◽

Author(s):

Ernesto Callegari ◽

Jian Lin ◽

Susanna Tse ◽

Theunis C. Goosen ◽

Vaishali Sahasrabudhe

Keyword(s):

Drug Interaction ◽

Mefenamic Acid ◽

Physiologically Based ◽

Model-Based Assessments of CYP-Mediated Drug-Drug Interaction Risk of Alectinib: Physiologically Based Pharmacokinetic Modeling Supported Clinical Development

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.956 ◽

2017 ◽

Vol 104 (3) ◽

pp. 505-514 ◽

Cited By ~ 4

Author(s):

Yumi Cleary ◽

Michael Gertz ◽

Peter N. Morcos ◽

Li Yu ◽

Kuresh Youdim ◽

...

Keyword(s):

Drug Interaction ◽

Clinical Development ◽

Model Based ◽

Physiologically Based ◽

Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Simulation and Prediction of the Drug‐Drug Interaction Potential of Naloxegol by Physiologically Based Pharmacokinetic Modeling

10.1002/psp4.12070 ◽

2016 ◽

Vol 5 (5) ◽

pp. 250-257 ◽

Cited By ~ 22

Author(s):

D Zhou ◽

K Bui ◽

M Sostek ◽

N Al‐Huniti

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Physiologically Based ◽

Assessing drug interaction risk of the grapefruit juice component and dietary supplement 6′,7′‐dihydroxybergamottin via physiologically‐based pharmacokinetic modeling and simulation

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.1103.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Garrett Robert Ainslie ◽

Brandon T Gufford ◽

Christina S Won ◽

Kristina K Wolf ◽

Mary F Paine

Keyword(s):

Drug Interaction ◽

Modeling And Simulation ◽

Dietary Supplement ◽

Grapefruit Juice ◽

Pharmacokinetic Modeling And Simulation

Physiologically Based ◽