Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug–Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir

2015 ◽  
Vol 55 (5) ◽  
pp. 605-613 ◽  
Author(s):  
Erik Mogalian ◽  
Polina German ◽  
Brian P. Kearney ◽  
Cheng Yong Yang ◽  
Diana Brainard ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interaction ◽  
Interaction Potential ◽  
Ns5a Inhibitor ◽  
Drug Drug Interaction

scholarly journals A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug-Drug Interaction Potential of the Cytotoxic Prodrug Evofosfamide

2018 ◽  
Vol 7 (12) ◽  
pp. 829-837 ◽  
Author(s):  
Christian Lüpfert ◽  
Martin Dyroff ◽  
Oliver von Richter ◽  
Dieter Gallemann ◽  
Samer El Bawab ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interaction ◽  
Interaction Potential ◽  
Pbpk Modeling ◽  
Modeling Approach ◽  
Drug Drug Interaction

scholarly journals Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

2020 ◽  
Vol 319 ◽  
pp. 148-154 ◽  
Author(s):  
Shyam H. Kamble ◽  
Abhisheak Sharma ◽  
Tamara I. King ◽  
Erin C. Berthold ◽  
Francisco León ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interaction ◽  
Interaction Potential ◽  
Drug Drug Interaction

Pomalidomide: Evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects

2014 ◽  
Vol 55 (2) ◽  
pp. 168-178 ◽  
Author(s):  
Claudia Kasserra ◽  
Mahmoud Assaf ◽  
Matthew Hoffmann ◽  
Yan Li ◽  
Liangang Liu ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interaction ◽  
Interaction Potential ◽  
Healthy Subjects ◽  
Drug Drug Interaction
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