Assessment of cytochrome P450-mediated drug-drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinetic modeling and simulation

Physiologically Based ◽

Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Evaluation of the Drug–Drug Interaction Potential of Acalabrutinib and Its Active Metabolite, ACP ‐5862, Using a Physiologically‐Based Pharmacokinetic Modeling Approach

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12408 ◽

2019 ◽

Vol 8 (7) ◽

pp. 489-499 ◽

Cited By ~ 1

Author(s):

Diansong Zhou ◽

Terry Podoll ◽

Yan Xu ◽

Ganesh Moorthy ◽

Karthick Vishwanathan ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Active Metabolite ◽

Modeling Approach ◽

Physiologically Based ◽

Simulation and Prediction of the Drug‐Drug Interaction Potential of Naloxegol by Physiologically Based Pharmacokinetic Modeling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12070 ◽

2016 ◽

Vol 5 (5) ◽

pp. 250-257 ◽

Cited By ~ 22

Author(s):

D Zhou ◽

K Bui ◽

M Sostek ◽

N Al‐Huniti

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Physiologically Based ◽

Applications of Physiologically Based Pharmacokinetic Modeling of Rivaroxaban—Renal and Hepatic Impairment and Drug‐Drug Interaction Potential

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1784 ◽

2021 ◽

Author(s):

Stefan Willmann ◽

Katrin Coboeken ◽

Stefanie Kapsa ◽

Kirstin Thelen ◽

Markus Mundhenke ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Hepatic Impairment ◽

Physiologically Based ◽

Prediction of drug–drug interaction potential using physiologically based pharmacokinetic modeling

Archives of Pharmacal Research ◽

10.1007/s12272-017-0976-0 ◽

2017 ◽

Vol 40 (12) ◽

pp. 1356-1379 ◽

Cited By ~ 18

Author(s):

Jee Sun Min ◽

Soo Kyung Bae

Keyword(s):

Drug Interaction ◽

Interaction Potential ◽

Physiologically Based ◽

Physiologically‐Based Pharmacokinetic Modeling for the Prediction of a Drug–Drug Interaction of Combined Effects on P‐glycoprotein and Cytochrome P450 3A

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12562 ◽

2020 ◽

Vol 9 (11) ◽

pp. 659-669

Author(s):

Yukio Otsuka ◽

Mary P. Choules ◽

Peter L. Bonate ◽

Kanji Komatsu

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Combined Effects ◽

Cytochrome P450 3A ◽

P Glycoprotein ◽

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug–Drug Interaction Potentials

Pharmaceutical Research ◽

10.1007/s11095-018-2511-5 ◽

2018 ◽

Vol 35 (12) ◽

Author(s):

Su-jin Rhee ◽

Hyun A. Lee ◽

Soyoung Lee ◽

Eunwoo Kim ◽

Inseung Jeon ◽

...

Keyword(s):

Drug Interaction ◽

Interaction Potentials ◽

Physiologically Based ◽

Physiologically based pharmacokinetic modeling for assessing the clinical drug–drug interaction of alisporivir

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2014.06.021 ◽

2014 ◽

Vol 63 ◽

pp. 103-112 ◽

Cited By ~ 8

Author(s):

Binfeng Xia ◽

Avantika Barve ◽

Tycho Heimbach ◽

Tao Zhang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interaction ◽

Physiologically Based ◽

Drug Drug Interaction ◽

Clinical Drug

Prediction of the Impact of Cytochrome P450 2C9 Genotypes on the Drug–Drug Interaction Potential of Siponimod With Physiologically‐Based Pharmacokinetic Modeling: A Comprehensive Approach for Drug Label Recommendations

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1547 ◽

2019 ◽

Vol 106 (5) ◽

pp. 1113-1124 ◽

Cited By ~ 4

Author(s):

Felix Huth ◽

Anne Gardin ◽

Kenichi Umehara ◽

Handan He

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Interaction Potential ◽

Comprehensive Approach ◽

Cytochrome P450 2C9 ◽

Drug Label ◽

Physiologically Based ◽

The Impact

Physiologically based pharmacokinetic modeling of the drug drug interaction between rifampin and SGLT2 inhibitors: The contribution of CYP induction to the observed interaction

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2017.11.168 ◽

2018 ◽

Vol 33 (1) ◽

pp. S48-S49

Author(s):

Ernesto Callegari ◽

Jian Lin ◽

Susanna Tse ◽

Theunis C. Goosen ◽

Vaishali Sahasrabudhe ◽

...

Keyword(s):

Drug Interaction ◽

Sglt2 Inhibitors ◽

Cyp Induction ◽

Physiologically Based ◽