Nitroimidazole and oxygen derived radicals detected by electron spin resonance in hydrogenosomal and cytosolic fractions from Trichomonas vaginalis

1987 ◽  
Vol 24 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Nigel Yarlett ◽  
Christopher C. Rowlands ◽  
Jeffrey C. Evans ◽  
Nuriza C. Yarlett ◽  
David Lloyd
Keyword(s):  
Electron Spin Resonance ◽  
Electron Spin ◽  
Trichomonas Vaginalis ◽  
Spin Resonance ◽  
Oxygen Derived Radicals

Reduction of niridazole by metronidazole resistant and susceptible strains of Trichomonas vaginalis

Parasitology ◽  
1987 ◽  
Vol 94 (1) ◽  
pp. 93-99 ◽  
Author(s):  
N. Yarlett ◽  
C. C. Rowlands ◽  
Nuriza C. Yarlett ◽  
J. C. Evans ◽  
D. Lloyd
Keyword(s):  
Electron Spin Resonance ◽  
Hydrogen Production ◽  
Electron Spin ◽  
Trichomonas Vaginalis ◽  
Fold Increase ◽  
Inhibitory Effect ◽  
Resistant Isolate ◽  
Fold Reduction ◽  
Spin Resonance

SUMMARYThe inhibitory effect of niridazole on hydrogen production by metronidazole-resistant (CDC-85) and susceptible (Cl-NIH) Trichomonas vaginalis strains was investigated. The results show that niridazole is more effective than metronidazole in inhibiting hydrogen production by the resistant isolate. In CDC-85 aerobic inhibition requires a 4-fold increase in metronidazole concentration compared with that required anaerobically, but the corresponding factor for niridazole is only 1·5-fold. Reduction of the drug by a hydrogenosome-enriched preparation gave rise to a multiline electron spin resonance detectable signal, which is due to a nitrogen-centred radical.

scholarly journals Detection of Oxygen-Derived Radicals in Biological Systems Using Electron Spin Resonance

1994 ◽  
Vol 102 ◽  
pp. 33 ◽  
Author(s):  
Ronald P. Mason ◽  
Phillip M. Hanna ◽  
Mark J. Burkitt ◽  
Maria B. Kadiiska
Keyword(s):  
Electron Spin Resonance ◽  
Electron Spin ◽  
Biological Systems ◽  
Spin Resonance ◽  
Oxygen Derived Radicals

Electron spin resonance of palladium-related defect in silicon

2009 ◽  
Vol 404 (23-24) ◽  
pp. 4586-4589
Author(s):  
T. Ishiyama ◽  
S. Kimura ◽  
Y. Kamiura ◽  
Y. Yamashita
Keyword(s):  
Electron Spin Resonance ◽  
Electron Spin ◽  
Spin Resonance ◽  
Related Defect
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