Tracking the polymerization of DNA sensors and inflammasomes using FRET

2019 ◽  
pp. 87-94
Author(s):  
Zachary Mazanek ◽  
Jungsan Sohn
Keyword(s):  
Dna Sensors

Nanoprobes for enhanced electrochemical DNA sensors

2015 ◽  
Vol 7 (6) ◽  
pp. 817-827 ◽  
Author(s):  
Rosa Letizia Zaffino ◽  
Teresa Galan ◽  
Wilmer Alfonso Pardo ◽  
Mònica Mir ◽  
Josep Samitier
Keyword(s):  
Dna Sensors

Sequence-Specific Label-Free DNA Sensors Based on Silicon Nanowires

Nano Letters ◽  
2004 ◽  
Vol 4 (2) ◽  
pp. 245-247 ◽  
Author(s):  
Z. Li ◽  
Y. Chen ◽  
X. Li ◽  
T. I. Kamins ◽  
K. Nauka ◽  
...  
Keyword(s):  
Silicon Nanowires ◽  
Label Free ◽  
Dna Sensors ◽  
Free Dna ◽  
Specific Label

scholarly journals Disposable Magnetic DNA Sensors for the Determination at the Attomolar Level of a SpecificEnterobacteriaceaeFamily Gene

2008 ◽  
Vol 80 (21) ◽  
pp. 8239-8245 ◽  
Author(s):  
Óscar A. Loaiza ◽  
Susana Campuzano ◽  
María Pedrero ◽  
M. Isabel Pividori ◽  
Pedro García ◽  
...  
Keyword(s):  
Dna Sensors

Toward intelligent polymers: DNA sensors based on oligonucleotide-functionalized polypyrroles

1999 ◽  
Vol 100 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Francis Garnier ◽  
Hafsa Korri-Youssoufi ◽  
Pratima Srivastava ◽  
Bernard Mandrand ◽  
Thierry Delair
Keyword(s):  
Dna Sensors ◽  
Intelligent Polymers

A novel bio-functionalization of AlGaN/GaN-ISFETs for DNA-sensors

2010 ◽  
Vol 7 (7-8) ◽  
pp. 1810-1813 ◽  
Author(s):  
Stefanie Linkohr ◽  
Stefan Schwarz ◽  
Stefan Krischok ◽  
Pierre Lorenz ◽  
Volker Cimalla ◽  
...  
Keyword(s):  
Dna Sensors

DNA Sensors for the Detection of Biomolecules and Biochemical Conditions

2017 ◽  
pp. 57-97
Author(s):  
Birgitta R. Knudsen ◽  
Anni H. Andersen ◽  
Magnus Stougaard ◽  
Giuseppe Arrabito ◽  
Raffaella Suriano ◽  
...  
Keyword(s):  
Dna Sensors ◽  
Detection Of Biomolecules

scholarly journals PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors

2018 ◽  
Vol 115 (15) ◽  
pp. 3930-3935 ◽  
Author(s):  
Dongshi Chen ◽  
Jingshan Tong ◽  
Liheng Yang ◽  
Liang Wei ◽  
Donna B. Stolz ◽  
...  
Keyword(s):  
Feedback Loop ◽  
Dependent Manner ◽  
Dna Sensors ◽  
Necrotic Cell ◽  
Developmental Defects ◽  
Tnf Α ◽  
Amplification Mechanism ◽  
Signaling Process

Necroptosis, a form of regulated necrotic cell death, is governed by RIP1/RIP3-mediated activation of MLKL. However, the signaling process leading to necroptotic death remains to be elucidated. In this study, we found that PUMA, a proapoptotic BH3-only Bcl-2 family member, is transcriptionally activated in an RIP3/MLKL-dependent manner following induction of necroptosis. The induction of PUMA, which is mediated by autocrine TNF-α and enhanced NF-κB activity, contributes to necroptotic death in RIP3-expressing cells with caspases inhibited. On induction, PUMA promotes the cytosolic release of mitochondrial DNA and activation of the DNA sensors DAI/Zbp1 and STING, leading to enhanced RIP3 and MLKL phosphorylation in a positive feedback loop. Furthermore, deletion of PUMA partially rescues necroptosis-mediated developmental defects in FADD-deficient embryos. Collectively, our results reveal a signal amplification mechanism mediated by PUMA and cytosolic DNA sensors that is involved in TNF-driven necroptotic death in vitro and in vivo.

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