Comparison of Descemet membrane endothelial keratoplasty for iridocorneal endothelial syndrome and Fuchs endothelial dystrophy

Author(s):  
Jing Wu ◽  
Xiaojuan Dong ◽  
Chen Ouyang ◽  
Jianping Ji ◽  
Lijie Xie ◽  
...  
Cornea ◽  
2017 ◽  
Vol 36 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Thomas M. Müller ◽  
Itay Lavy ◽  
Lamis Baydoun ◽  
Jessica T. Lie ◽  
Isabel Dapena ◽  
...  

Author(s):  
Tibor Lohmann ◽  
Sabine Baumgarten ◽  
Niklas Plange ◽  
Peter Walter ◽  
Matthias Fuest

Abstract Purpose To determine retinal thickness (RT) changes and the incidence of macular edema after uncomplicated Descemet membrane endothelial keratoplasty (DMEK-ME) in patients without ME risk factors. Methods In this retrospective study, 107 pseudophakic eyes of 74 patients with Fuchs endothelial dystrophy (FED) (79.4%) or bullous keratopathy (BK) (20.6%) underwent DMEK surgery between 2016 and 2019 at the Department of Ophthalmology, RWTH Aachen University. Patients with intra- or postoperative complications as well as pre-existing risk factors for ME were excluded. Macular spectral-domain optical coherence tomography (SD-OCT) and best spectacle-corrected visual acuity (BSCVA) measurements were performed before, 1 week, 1 month, and 6 months after surgery. Retinal thickness (RT) was analyzed in the central foveal 1 mm (CSF), parafoveal 3 mm and 6 mm subfield. Results Eight eyes (7.5%) developed DMEK-ME 1 month after surgery. Six DMEK-ME eyes (75%) were rebubbled, compared with 31.3% (31 of 99; P = 0.02) of the non DMEK-ME eyes. DMEK-ME eyes had a significantly thicker CSF 1 month after surgery (432.0 ± 97.6 μm) compared with non-DMEK-ME eyes (283.7 ± 22.2 μm; P = 0.01). The other subfields and time points showed no significant RT changes. DMEK-ME significantly impaired BSCVA (0.38 ± 0.92 logMAR) only 1 month after surgery in comparison to the non DMEK-ME eyes (0.23 ± 0.87 logMAR, P = 0.015). Conclusion Excluding systemic and surgery-related risk factors, rebubbling increases the risk of DMEK-ME. Performing a CSF scan 1 month after surgery, particularly in rebubbled eyes, efficiently detects DMEK-ME and allows the prompt initiation of treatment, e.g., topical corticosteroid and non-steroidal (NSAID) eye drops.


Cornea ◽  
2014 ◽  
Vol 33 (10) ◽  
pp. 1010-1015 ◽  
Author(s):  
Javier Cabrerizo ◽  
Eitan Livny ◽  
Fayyaz U. Musa ◽  
Paulien Leeuwenburgh ◽  
Korine van Dijk ◽  
...  

Cornea ◽  
2018 ◽  
Vol 37 (7) ◽  
pp. 848-853
Author(s):  
Lamis Baydoun ◽  
Fook Chang Lam ◽  
Sontje Schaal ◽  
Shugi Hsien ◽  
Silke Oellerich ◽  
...  

2016 ◽  
Vol 100 (11) ◽  
pp. 1564-1568 ◽  
Author(s):  
Nadine Gerber-Hollbach ◽  
Jack Parker ◽  
Lamis Baydoun ◽  
Vasilios S Liarakos ◽  
Lisanne Ham ◽  
...  

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