Comparison of allergic rhinitis outcomes of the environmental exposure unit and nasal allergen challenge model

2019 ◽  
Vol 123 (1) ◽  
pp. 105-106.e1 ◽  
Author(s):  
Mark W. Tenn ◽  
Lisa M. Steacy ◽  
Daniel E. Adams ◽  
Terry J. Walker ◽  
Anne K. Ellis
Keyword(s):  
Allergic Rhinitis ◽  
Environmental Exposure ◽  
Allergen Challenge ◽  
Environmental Exposure Unit ◽  
Nasal Allergen Challenge

Eicosanoid Products in Nasal Rinses Obtained after Acute and Chronic Allergen Stimulation

1989 ◽  
Vol 3 (2) ◽  
pp. 69-76
Author(s):  
Carter D. Brooks ◽  
Kathleen J. Karl ◽  
Gordon J. White
Keyword(s):  
Allergic Rhinitis ◽  
Environmental Exposure ◽  
Allergen Challenge ◽  
Naturally Occurring ◽  
Nasal Provocation ◽  
Before And After ◽  
Nasal Allergen Challenge ◽  
Acute Challenge

To explore biochemical relationships between naturally occurring allergic rhinitis and a nasal provocation model, we measured PGD2 and LTC4 content of nasal rinses obtained before and after nasal allergen challenge, in and out of the allergy season. Both PGD2 and LTC4 contents rose after challenge. The rise in season was substantially greater than that seen out of season, and the amounts of eicosanoids present after acute challenge out of season were greater than those recovered when the patients were symptomatic in season. Eicosanoid response is quantitatively different with chronic environmental exposure and with acute laboratory provocation.

scholarly journals A Replicate Study Utilizing Two Controlled Allergen Challenge Facilities – The Environmental Exposure Unit and the Biogenics Research Chamber.

2017 ◽  
Vol 139 (2) ◽  
pp. AB159
Author(s):  
Anne K. Ellis ◽  
Lisa M. Steacy ◽  
Alkis Togias ◽  
Charles P. Andrews ◽  
Daniel A. Ramirez ◽  
...  
Keyword(s):  
Environmental Exposure ◽  
Allergen Challenge ◽  
Environmental Exposure Unit

scholarly journals Reproducibility of nasal allergen challenge responses in adults with allergic rhinitis

2019 ◽  
Vol Volume 11 ◽  
pp. 67-76
Author(s):  
Charles T. Pantin ◽  
Thomas Southworth ◽  
Kristiane Wetzel ◽  
Dave Singh
Keyword(s):  
Allergic Rhinitis ◽  
Allergen Challenge ◽  
Nasal Allergen Challenge
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