scholarly journals First Finite Element Model of the Left Ventricle With Mitral Valve: Insights Into Ischemic Mitral Regurgitation

2010 ◽  
Vol 89 (5) ◽  
pp. 1546-1553 ◽  
Author(s):  
Jonathan F. Wenk ◽  
Zhihong Zhang ◽  
Guangming Cheng ◽  
Deepak Malhotra ◽  
Gabriel Acevedo-Bolton ◽  
...  
1983 ◽  
Vol 16 (1) ◽  
pp. 45-58 ◽  
Author(s):  
Alan Needleman ◽  
Stuart A. Rabinowitz ◽  
Daniel K. Bogen ◽  
Thomas A. McMahon

2019 ◽  
Vol 116 (3) ◽  
pp. 30a
Author(s):  
Charles K. Mann ◽  
Zhanqui Liu ◽  
Xiaoyan Zhang ◽  
Kenneth Campbell ◽  
Jonathan Wenk

Author(s):  
Chung-Hao Lee ◽  
Robert C. Gorman ◽  
Joseph H. Gorman ◽  
Rouzbeh Aimini ◽  
Michael S. Sacks

Many surgeons have come to view mitral valve (MV) repair as the treatment of choice in patients with mitral regurgitation (MR) [1]. According to recent long-term studies, the recurrence of significant MR after repair may be much higher than previously believed, particularly in patients with (ischemic mitral regurgitation) IMR [2]. We hypothesize that the restoration of homeostatic normal MV leaflet tissue stress in IMR repair techniques ultimately leads to improved repair durability. Therefore, the objective of this study is to develop a novel micro-anatomically accurate 3D finite element (FE) model that incorporates detailed collagen fiber architecture, accurate constitutive models, and micro-anatomically realistic valvular geometry to investigate the functional mitral valve and to aid in the assessment of the mitral valve repairs, especially the linking between the interstitial cellular deformations at the cellular level, the mechanobiological behaviors at the tissue level and the organ level mechanical responses as normal and repaired mitral valves maintaining their homeostatic state.


1991 ◽  
Vol 24 (7) ◽  
pp. 527-538 ◽  
Author(s):  
Jacques M. Huyghe ◽  
Dick H. van Campen ◽  
Theo Arts ◽  
Robert M. Heethaar

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