Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK

2013 ◽  
Vol 441 (2) ◽  
pp. 463-468 ◽  
Author(s):  
Paul D. Wright ◽  
Gregory Weir ◽  
Jamie Cartland ◽  
David Tickle ◽  
Catherine Kettleborough ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Pore Domain

scholarly journals TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family.

1999 ◽  
Vol 274 (34) ◽  
pp. 24440
Author(s):  
Raymond A. Chavez ◽  
Andrew T. Gray ◽  
Byron B. Zhao ◽  
Christoph H. Kindler ◽  
Matthew J. Mazurek ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Pore Domain

Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K2P9.1 (TASK-3)

ChemMedChem ◽  
2011 ◽  
Vol 7 (1) ◽  
pp. 123-133 ◽  
Author(s):  
Craig A. Coburn ◽  
Yunfu Luo ◽  
Mingxiang Cui ◽  
Jiabing Wang ◽  
Richard Soll ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Pharmacologically Active ◽  
Pore Domain

scholarly journals Molecular Modeling of a Tandem Two Pore Domain Potassium Channel Reveals a Putative Binding Site for General Anesthetics

2014 ◽  
Vol 5 (12) ◽  
pp. 1246-1252 ◽  
Author(s):  
Edward J. Bertaccini ◽  
Robert Dickinson ◽  
James R. Trudell ◽  
Nicholas P. Franks
Keyword(s):  
Molecular Modeling ◽  
Potassium Channel ◽  
Binding Site ◽  
General Anesthetics ◽  
Pore Domain ◽  
Putative Binding Site

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

2014 ◽  
Vol 67 ◽  
pp. 69-76 ◽  
Author(s):  
Bo Liang ◽  
Magdalena Soka ◽  
Alex Horby Christensen ◽  
Morten S. Olesen ◽  
Anders P. Larsen ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Potassium Channel ◽  
Pore Domain

Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS

Neuroscience ◽  
2001 ◽  
Vol 103 (4) ◽  
pp. 899-919 ◽  
Author(s):  
G.J Hervieu ◽  
J.E Cluderay ◽  
C.W Gray ◽  
P.J Green ◽  
J.L Ranson ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Adult Rat ◽  
Pore Domain ◽  
Rat Cns

scholarly journals Dynamics of Pore Domain Affected by Single Mutations in S4 Segment of Shaker Potassium Channel

2019 ◽  
Vol 116 (3) ◽  
pp. 101a
Author(s):  
Carlos Alberto ◽  
Z. Bassetto Jr ◽  
Joao Luis Carvalho-de-Souza ◽  
Francisco Bezanilla
Keyword(s):  
Potassium Channel ◽  
Shaker Potassium Channel ◽  
Pore Domain ◽  
S4 Segment

scholarly journals Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel

2014 ◽  
Vol 592 (14) ◽  
pp. 3013-3030 ◽  
Author(s):  
Qi Lei ◽  
Xiao-Qing Pan ◽  
Shaohua Chang ◽  
S. Bruce Malkowicz ◽  
Thomas J. Guzzo ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Pore Domain ◽  
Human Detrusor

Sepsis varies arterial two-pore-domain potassium channel messenger RNA in mice

2015 ◽  
Vol 193 (2) ◽  
pp. 816-824 ◽  
Author(s):  
Florian Bieling ◽  
Florian Uhle ◽  
Katja Weissmüller ◽  
Markus Alexander Weigand ◽  
Michael Henrich
Keyword(s):  
Potassium Channel ◽  
Messenger Rna ◽  
Pore Domain

Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K+Channel 1). A Novel Therapeutic Target?

2015 ◽  
Vol 59 (11) ◽  
pp. 5149-5157 ◽  
Author(s):  
Delphine Vivier ◽  
Khalil Bennis ◽  
Florian Lesage ◽  
Sylvie Ducki
Keyword(s):  
Potassium Channel ◽  
Therapeutic Target ◽  
K Channel ◽  
Pore Domain ◽  
Novel Therapeutic
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