New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies

Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: Synthesis, cyclooxygenase inhibition, and nitric oxide release studies

10.1016/j.bmc.2007.12.006 ◽

2008 ◽

Vol 16 (6) ◽

pp. 3302-3308 ◽

Cited By ~ 14

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Qiao-Hong Chen ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Donor ◽

Cyclooxygenase Inhibition ◽

Nitric Oxide Release ◽

Release Studies ◽

Anti Inflammatory ◽

Acrylic Acids ◽

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: Synthesis, nitric oxide release studies and anti-inflammatory activities

10.1016/j.bmc.2008.05.028 ◽

2008 ◽

Vol 16 (13) ◽

pp. 6528-6534 ◽

Cited By ~ 21

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Carboxylic Acids ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Release Studies ◽

Anti Inflammatory ◽

Faculty Opinions recommendation of Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011708.323215 ◽

2005 ◽

Author(s):

Larry K Keefer

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nonsteroidal Antiinflammatory Drugs ◽

Nitric Oxide Donor ◽

Antiinflammatory Drugs ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies

Rofecoxib Analogues Possessing a Nitric Oxide Donor Sulfohydroxamic Acid (SO2NHOH) Cyclooxygenase-2 Pharmacophore: Synthesis, Molecular Modeling, and Biological Evaluation as Anti-inflammatory Agents

ChemMedChem ◽

10.1002/cmdc.201100393 ◽

2011 ◽

Vol 7 (1) ◽

pp. 62-67 ◽

Cited By ~ 19

Author(s):

Atul Bhardwaj ◽

Zhangjian Huang ◽

Jatinder Kaur ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Molecular Modeling ◽

Biological Evaluation ◽

Cyclooxygenase 2 ◽

Nitric Oxide Donor ◽

Anti Inflammatory

Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: Design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies

10.1016/j.bmc.2007.07.021 ◽

2007 ◽

Vol 15 (21) ◽

pp. 6796-6801 ◽

Cited By ~ 14

Author(s):

Khaled R.A. Abdellatif ◽

Ying Dong ◽

Qiao-Hong Chen ◽

Morshed Alam Chowdhury ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Design Synthesis ◽

Cyclooxygenase Inhibition ◽

Nitric Oxide Release ◽

Release Studies ◽

Acrylic Ester ◽

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmc.2008.10.001 ◽

2008 ◽

Vol 16 (22) ◽

pp. 9694-9698 ◽

Cited By ~ 25

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Carlos Velázquez ◽

Dipankar Das ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Analog Synthesis ◽

Release Studies ◽

Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies

10.1016/j.bmc.2009.05.046 ◽

2009 ◽

Vol 17 (14) ◽

pp. 5182-5188 ◽

Cited By ~ 21

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Dipankar Das ◽

Gang Yu ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Analog Synthesis ◽

Release Studies ◽

Second-Generation Aspirin and Indomethacin Prodrugs Possessing anO2-(Acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate Nitric Oxide Donor Moiety: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Journal of Medicinal Chemistry ◽

10.1021/jm701450q ◽

2008 ◽

Vol 51 (6) ◽

pp. 1954-1961 ◽

Cited By ~ 45

Author(s):

Carlos A. Velázquez ◽

Qiao-Hong Chen ◽

Michael L. Citro ◽

Larry K. Keefer ◽

Edward E. Knaus

Keyword(s):

Nitric Oxide ◽

Second Generation ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Donor Moiety

Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.04.059 ◽

2009 ◽

Vol 19 (11) ◽

pp. 3014-3018 ◽

Cited By ~ 30

Author(s):

Khaled R.A. Abdellatif ◽

Morshed Alam Chowdhury ◽

Ying Dong ◽

Dipankar Das ◽

Gang Yu ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Nitric Oxide Donor ◽

Nitric Oxide Release ◽

Release Studies ◽

Novel Nitric Oxide-Releasing Derivatives of Brusatol as Anti-Inflammatory Agents: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Journal of Medicinal Chemistry ◽

10.1021/jm5007534 ◽

2014 ◽

Vol 57 (18) ◽

pp. 7600-7612 ◽

Cited By ~ 39

Author(s):

Weibin Tang ◽

Jianlin Xie ◽

Song Xu ◽

Haining Lv ◽

Mingbao Lin ◽

...

Keyword(s):

Nitric Oxide ◽

Biological Evaluation ◽

Design Synthesis ◽

Nitric Oxide Release ◽

Release Studies ◽

Anti Inflammatory ◽

Nitric Oxide Releasing ◽

Derivatives Of