Design, synthesis and SAR of phenylamino-substituted 5,11-dihydro-dibenzo[a,d]cyclohepten-10-ones and 11H-dibenzo[b,f]oxepin-10-ones as p38 MAP kinase inhibitors

2010 ◽  
Vol 20 (10) ◽  
pp. 3074-3077 ◽  
Author(s):  
Angelika Dorn ◽  
Verena Schattel ◽  
Stefan Laufer
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors

scholarly journals Design, Synthesis, and Biological Evaluation of Chromone-Based p38 MAP Kinase Inhibitors

2011 ◽  
Vol 54 (20) ◽  
pp. 7427-7431 ◽  
Author(s):  
Christine Dyrager ◽  
Linda Nilsson Möllers ◽  
Linda Karlsson Kjäll ◽  
John Patrick Alao ◽  
Peter Dinér ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐ b ]Pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 2

ChemMedChem ◽  
2019 ◽  
Vol 14 (24) ◽  
pp. 2093-2101
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Hiromi Fukuda ◽  
Rei Okamoto ◽  
Shinji Morimoto ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure‐Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5‐ b ]pyridin‐2‐one‐Based p38 MAP Kinase Inhibitors: Part 1

ChemMedChem ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. 1022-1030 ◽  
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Hiromi Fukuda ◽  
Rei Okamoto ◽  
Shinji Morimoto ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors

2018 ◽  
Vol 26 (3) ◽  
pp. 647-660 ◽  
Author(s):  
Akira Kaieda ◽  
Masashi Takahashi ◽  
Takafumi Takai ◽  
Masayuki Goto ◽  
Takahiro Miyazaki ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors ◽  
Synthesis And Biological Evaluation

2-Acylaminopyridin-4-ylimidazoles as p38 MAP Kinase Inhibitors: Design, Synthesis, and Biological and Metabolic Evaluations

ChemMedChem ◽  
2009 ◽  
Vol 4 (11) ◽  
pp. 1939-1948 ◽  
Author(s):  
Katharina Ziegler ◽  
Dominik R. J. Hauser ◽  
Anke Unger ◽  
Wolfgang Albrecht ◽  
Stefan A. Laufer
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
P38 Map Kinase ◽  
Design Synthesis ◽  
P38 Map Kinase Inhibitors

scholarly journals Inhibition of Wnt/β-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase Iδ/ɛ

2011 ◽  
Vol 18 (4) ◽  
pp. 485-494 ◽  
Author(s):  
Folkert Verkaar ◽  
Antoon A. van der Doelen ◽  
Jos F.M. Smits ◽  
W. Matthijs Blankesteijn ◽  
Guido J.R. Zaman
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Cross Reactivity ◽  
P38 Map Kinase ◽  
Casein Kinase ◽  
P38 Map Kinase Inhibitors

p38 MAP kinase inhibitors. Part 3: SAR on 3,4-dihydropyrimido[4,5-d]pyrimidin-2-ones and 3,4-dihydropyrido[4,3-d]pyrimidin-2-ones

2006 ◽  
Vol 16 (16) ◽  
pp. 4400-4404 ◽  
Author(s):  
Swaminathan R. Natarajan ◽  
David D. Wisnoski ◽  
James E. Thompson ◽  
Edward A. O’Neill ◽  
Stephen J. O’Keefe
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
P38 Map Kinase ◽  
P38 Map Kinase Inhibitors
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