Inosine monophosphate dehydrogenase activity depends on plasma concentrations of mycophenolic acid and its glucuronides in kidney transplant recipients

Clinica Chimica Acta ◽

10.1016/j.cca.2009.08.016 ◽

2009 ◽

Vol 409 (1-2) ◽

pp. 56-61 ◽

Author(s):

Yasuaki Mino ◽

Takafumi Naito ◽

Atsushi Otsuka ◽

Seiichiro Ozono ◽

Yoshiyuki Kagawa ◽

...

Keyword(s):

Dehydrogenase Activity ◽

Kidney Transplant ◽

Mycophenolic Acid ◽

Plasma Concentrations ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

Inosine Monophosphate ◽

Monophosphate Dehydrogenase

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Inosine Monophosphate Dehydrogenase (IMPDH) Activity as a Pharmacodynamic Biomarker of Mycophenolic Acid Effects in Pediatric Kidney Transplant Recipients

The Journal of Clinical Pharmacology ◽

10.1177/0091270010368542 ◽

2011 ◽

Vol 51 (3) ◽

pp. 309-320 ◽

Author(s):

Tsuyoshi Fukuda ◽

Jens Goebel ◽

Håvard Thøgersen ◽

Denise Maseck ◽

Shareen Cox ◽

...

Keyword(s):

Kidney Transplant ◽

Mycophenolic Acid ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

Inosine Monophosphate ◽

Impdh Activity ◽

Monophosphate Dehydrogenase

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Effect of Diabetes Mellitus on Mycophenolate Sodium Pharmacokinetics and Inosine Monophosphate Dehydrogenase Activity in Stable Kidney Transplant Recipients

Therapeutic Drug Monitoring ◽

10.1097/ftd.0b013e31815d8ace ◽

2007 ◽

Vol 29 (6) ◽

pp. 735-742 ◽

Author(s):

Chirag G Patel ◽

Katherine Richman ◽

Dongfang Yang ◽

Bingfang Yan ◽

Reginald Y Gohh ◽

...

Keyword(s):

Diabetes Mellitus ◽

Dehydrogenase Activity ◽

Kidney Transplant ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

Inosine Monophosphate ◽

Mycophenolate Sodium ◽

Monophosphate Dehydrogenase

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Inosine Monophosphate Dehydrogenase Expression and Activity Are Significantly Lower in Kidney Transplant Recipients With Diabetes Mellitus

Therapeutic Drug Monitoring ◽

10.1097/ftd.0b013e3182852697 ◽

2013 ◽

Vol 35 (3) ◽

pp. 374-383 ◽

Author(s):

Miroslav Dostalek ◽

Reginald Y. Gohh ◽

Fatemeh Akhlaghi

Keyword(s):

Diabetes Mellitus ◽

Kidney Transplant ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

Inosine Monophosphate ◽

Expression And Activity ◽

Monophosphate Dehydrogenase

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MONITORING INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) ACTIVITY IN KIDNEY TRANSPLANT RECIPIENTS

Transplantation Journal ◽

10.1097/00007890-201007272-01208 ◽

2010 ◽

Vol 90 ◽

pp. 633

Author(s):

M. Molinaro ◽

L. R. Chiarelli ◽

C. Libetta ◽

C. Tinelli ◽

L. Cosmai ◽

...

Keyword(s):

Kidney Transplant ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Kidney Transplant Recipients ◽

Inosine Monophosphate ◽

Impdh Activity ◽

Monophosphate Dehydrogenase

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GTP Concentrations are Elevated in Erythrocytes of Renal Transplant Recipients when Conventional Immunosuppression is Replaced by the Inosine Monophosphate Dehydrogenase Inhibitor Mycophenolic Acid Mofetil (MMF)

Nucleosides Nucleotides & Nucleic Acids ◽

10.1081/ncn-200027645 ◽

2004 ◽

Vol 23 (8-9) ◽

pp. 1407-1409 ◽

Author(s):

D. J. A. Goldsmith ◽

E. A. Carrey ◽

S. M. Edbury ◽

A. M. Marinaki ◽

H. A. Simmonds

Keyword(s):

Renal Transplant ◽

Mycophenolic Acid ◽

Renal Transplant Recipients ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Inosine Monophosphate ◽

Conventional Immunosuppression ◽

Monophosphate Dehydrogenase

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GTP Concentrations Are Elevated in Erythrocytes of Renal Transplant Recipients when Conventional Immunosuppression Is Replaced by the Inosine Monophosphate Dehydrogenase Inhibitor Mycophenolic Acid Mofetil (MMF)

10.1002/chin.200511217 ◽

2005 ◽

Vol 36 (11) ◽

Author(s):

D. J. A. Goldsmith ◽

E. A. Carrey ◽

S. M. Edbury ◽

A. M. Marinaki ◽

H. A. Simmonds

Keyword(s):

Renal Transplant ◽

Mycophenolic Acid ◽

Renal Transplant Recipients ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Inosine Monophosphate ◽

Conventional Immunosuppression ◽

Monophosphate Dehydrogenase

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Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid

European Journal of Clinical Pharmacology ◽

10.1007/s00228-011-1203-4 ◽

2012 ◽

Vol 68 (6) ◽

pp. 913-922 ◽

Author(s):

A. Rother ◽

P. Glander ◽

E. Vitt ◽

D. Czock ◽

N. von Ahsen ◽

...

Keyword(s):

Dehydrogenase Activity ◽

Mycophenolic Acid ◽

Inosine Monophosphate Dehydrogenase ◽

Inosine Monophosphate ◽

Age Related ◽

Monophosphate Dehydrogenase

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Mycophenolate pharmacokinetics and inosine monophosphate dehydrogenase activity in liver transplant recipients with an emphasis on therapeutic drug monitoring

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365513.2012.745947 ◽

2013 ◽

Vol 73 (2) ◽

pp. 117-124 ◽

Author(s):

Pål A. Reine ◽

Nils T. Vethe ◽

Ulf E. Kongsgaard ◽

Anders M. Andersen ◽

Pål D. Line ◽

...

Keyword(s):

Therapeutic Drug Monitoring ◽

Liver Transplant ◽

Dehydrogenase Activity ◽

Drug Monitoring ◽

Therapeutic Drug ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Inosine Monophosphate ◽

Liver Transplant Recipients ◽

Monophosphate Dehydrogenase

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Inhibition of Inosine Monophosphate Dehydrogenase Activity by the Plasma of Heart Transplant Recipients Receiving Mycophenolate Mofetil

Advances in Experimental Medicine and Biology - Purine and Pyrimidine Metabolism in Man IX ◽

10.1007/978-1-4615-5381-6_104 ◽

1998 ◽

pp. 537-541 ◽

Author(s):

Andrea Griesmacher ◽

Günter Weigel ◽

Gernot Seebacher ◽

R. Mallinger ◽

Günther Laufer ◽

...

Keyword(s):

Mycophenolate Mofetil ◽

Dehydrogenase Activity ◽

Heart Transplant ◽

Inosine Monophosphate Dehydrogenase ◽

Transplant Recipients ◽

Inosine Monophosphate ◽

Heart Transplant Recipients ◽

Monophosphate Dehydrogenase

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Inosine Monophosphate Dehydrogenase Messenger RNA Expression Is Correlated to Clinical Outcomes in Mycophenolate Mofetil-Treated Kidney Transplant Patients, Whereas Inosine Monophosphate Dehydrogenase Activity Is Not

Therapeutic Drug Monitoring ◽

10.1097/ftd.0b013e3181b7a9d0 ◽

2009 ◽

Vol 31 (5) ◽

pp. 549-556 ◽

Author(s):

Ferdi Sombogaard ◽

Annemiek M A Peeters ◽

Carla C Baan ◽

Ron A A Mathot ◽

Monique E Quaedackers ◽

...

Keyword(s):

Mycophenolate Mofetil ◽

Dehydrogenase Activity ◽

Kidney Transplant ◽

Messenger Rna ◽

Rna Expression ◽

Inosine Monophosphate Dehydrogenase ◽

Inosine Monophosphate ◽

Transplant Patients ◽

Kidney Transplant Patients ◽

Monophosphate Dehydrogenase

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